Protective role of black tea against oxidative damage of human red blood cells

Biochemical and Biophysical Research Communications
J Halder, A Bhaduri

Abstract

The purpose of our study was to explore the possible scavenging property of black tea and catechins, the major flavonols of tea-leaf, against damage by oxidative stress. For this purpose, human red blood cell (rbc) was taken as the model and the oxidative damage was induced by a variety of inducers, e.g. phenylhydrazine (PHX), Cu(2+)-ascorbic acid, and xanthine/xanthine oxidase systems. Lipid peroxidation of pure erythrocyte membrane and of whole red blood cell could be completely prevented by black tea extract. Similarly, black tea provided total protection against degradation of membrane proteins. Finally, membrane fluidity studies as monitored by the fluorescent probe 1,6 diphenyl hexa 1,3,5-triene (DPH) showed considerable disorganization of its architecture that could be restored back to normal on addition of black tea or free catechins. Black tea extract in comparison to free catechins seemed to be a better protecting agent against various types of oxidative stress. Apparently, conversion of catechins to partially polymerized products such as theaflavin or thearubigin during 'fermentation' process for making black tea has no deleterious effect on its scavenging properties.

References

Apr 30, 1990·Biochimica Et Biophysica Acta·D PradhanR A Schlegel
Jul 31, 1980·Biochemical and Biophysical Research Communications·M K BasuA Maniatis
Jun 1, 1981·Biochemical and Biophysical Research Communications·C Rice-Evans, P Hochstein
Jul 7, 1993·Journal of the National Cancer Institute·C S Yang, Z Y Wang
Jun 5, 1997·Nature·J JankunE Skrzypczak-Jankun
Jan 1, 1963·Archives of Biochemistry and Biophysics·J T DODGED J HANAHAN

❮ Previous
Next ❯

Citations

Apr 29, 2009·Critical Reviews in Food Science and Nutrition·Vasundhara Sharma, L Jagan Mohan Rao
Aug 30, 2000·Drug Metabolism and Drug Interactions·D Sür-Altiner, B Yenice
Apr 5, 2012·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·S A MendanhaA Alonso
Nov 26, 2010·Pharmacological Reports : PR·Adikesavan Gokulakrishnan, Abdul Rahman Liyakath Ali
Dec 17, 2008·Nutrition Research·Kettelin A ArbosAlmeriane M Weffort-Santos
May 3, 2008·Chemico-biological Interactions·Nandita Singh, P S Rajini
Jul 30, 2010·Journal of Animal Physiology and Animal Nutrition·B KróliczewskaJ Króliczewski
Sep 3, 2004·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Tzong-Der WayJen-Kun Lin
Feb 9, 2006·Brain Research Bulletin·Angelo Del ParigiVincenzo Solfrizzi
May 21, 2013·Biochemical and Biophysical Research Communications·Yong-Na ZhaoJun Gao
Nov 24, 2007·Biochimica Et Biophysica Acta·Sangeeta AdakMaitree Bhattacharyya
Jun 30, 2011·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·José I Sánchez-GallegoMarcial Llanillo
Dec 24, 2010·Journal of Asian and African Studies·Shah Nawaz
Nov 5, 2003·Phytotherapy Research : PTR·Talal Aburjai, Feda M Natsheh
Mar 3, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Wojciech KochŁukasz Komsta
Dec 15, 2005·Molecular Carcinogenesis·Hideya MizunoZigang Dong
Aug 22, 2009·Toxicology Mechanisms and Methods·Barbara Szachowicz-PetelskaZbigniew A Figaszewski
May 19, 2000·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·I Cantuti-CastelvetriJ A Joseph
Jun 12, 2009·Journal of Hypertension·Davide GrassiClaudio Ferri
Nov 9, 2017·Oncotarget·Xiangbing MaoJun He
Mar 10, 2012·Applied Biochemistry and Biotechnology·M NadourF Moulti-Mati
Jul 31, 2003·The Journal of Nutrition·Anup MisraIndu B Chatterjee
Jun 1, 2008·Comprehensive Reviews in Food Science and Food Safety·M G SajilataR S Singhal
Sep 21, 2000·Mechanisms of Ageing and Development·J A JosephB Shukitt-Hale
Jul 30, 2002·Prostaglandins, Leukotrienes, and Essential Fatty Acids·S HreliaP L Biagi
Aug 2, 2003·Archives of Biochemistry and Biophysics·D ErbaG Testolin
Sep 5, 2006·Archives of Biochemistry and Biophysics·Laura Pérez-FonsVicente Micol
Sep 20, 2000·Journal of Agricultural and Food Chemistry·T G ToschiP L Biagi
Dec 4, 2003·Journal of Agricultural and Food Chemistry·Kenichi YanagimotoTakayuki Shibamoto

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.