Protein adsorption on implant metals with various deformed surfaces

Colloids and Surfaces. B, Biointerfaces
Zhongwei WangLijie Qiao

Abstract

The adsorption of proteins has great influence on the biocompatibility, lubrication and corrosion properties of implantable metals. The subsurface microstructure of metals can be easily changed during the manufacturing or service processes and it is easily ignored. The same chemical composition but with various surface microstructures can result in very different adsorption behaviour. In this study, mechanical polishing, electrochemical polishing and shot peening methods were used to generate different gradient deformed surfaces for CoCrMo alloys. The increase of the residual compressive stress and the decrease of grains to a nano-size on the deformed subsurface can effectively enhance the activity of metal atoms and improve the element diffusion, that is helpful in forming a more compact passive film. This can increase the contents of oxides on the surface, and then enhance the electrostatic force and increase the surface's positive charge density as well as adsorption sites. All of the above facilitated the adsorption of the negatively charged albumin onto the alloy surface.

Citations

Jan 30, 2020·Biomaterials Science·Haifeng Fan, Zhiguang Guo
May 2, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Peter HollowellJian R Lu
Aug 28, 2020·APL Bioengineering·Wenzhen ZhuDong-An Wang
Jan 19, 2021·Colloids and Surfaces. B, Biointerfaces·Nicholas G Fischer, Conrado Aparicio
Jun 3, 2021·Journal of Functional Biomaterials·Astrid H Paulitsch-FuchsBirgit Lohberger
Dec 22, 2020·ACS Biomaterials Science & Engineering·Daniel WojtasKrzysztof Sztwiertnia
Feb 23, 2020·Langmuir : the ACS Journal of Surfaces and Colloids·Nicholas A MoringoChristy F Landes

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