Protein and peptide arrays: recent trends and new directions

Biomolecular Engineering
Marina CretichMarcella Chiari

Abstract

Microarrays of proteins and peptides make it possible the screening of thousands of binding events in a parallel and high throughput fashion; therefore they are emerging as a powerful tool for proteomics and clinical assays. The complex nature of Proteome, the wide dynamic range of protein concentration in real samples and the critical role of immobilized protein orientation must be taken into account to maximize the utility of protein microarrays. Immobilization strategy and designing of an ideal local chemical environment on the solid surface are both essential for the success of a protein microarray experiment. This review article will focus on protein and peptide arrays highlighting their technical challenges and presenting new directions by means of a set of selected recent applications.

References

Feb 8, 2000·Analytical Biochemistry·P ArenkovA Mirzabekov
Jun 28, 2000·Nucleic Acids Research·V AfanassievS Wölfl
Oct 6, 2000·Methods : a Companion to Methods in Enzymology·J E Butler
Jan 16, 2002·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Reinhard HillerRudolf Valenta
Feb 6, 2002·Chembiochem : a European Journal of Chemical Biology·R BentersD Wöhrle
Feb 9, 2002·Science·Ki-Bum LeeMilan Mrksich
Mar 5, 2002·Nature Biotechnology·Benjamin T HousemanMilan Mrksich
Mar 5, 2002·Nature Medicine·William H RobinsonPaul J Utz
Jul 18, 2002·Nature Reviews. Drug Discovery·Kevin BraeckmansJoseph Demeester
Jul 20, 2002·Bioorganic & Medicinal Chemistry Letters·Marie Laure LesaicherreShao Q Yao
Sep 26, 2002·Electrophoresis·Michael SchaeferlingDev Kambhampati
Jan 22, 2003·Luminescence : the Journal of Biological and Chemical Luminescence·Rick Wiese
Jan 28, 2003·Current Opinion in Chemical Biology·Heng Zhu, Michael Snyder
Feb 5, 2003·Current Opinion in Biotechnology·Stephen F Kingsmore, Dhavalkumar D Patel
Apr 12, 2003·Organic Letters·Qing ZhuShao Q Yao
May 3, 2003·Cancer Cell·Lance A LiottaEmanuel F Petricoin
Jun 20, 2003·Analytical Biochemistry·Zheng-liang ZhiEiichi Tamiya
Aug 5, 2003·Analytical and Bioanalytical Chemistry·Christophe A MarquetteLoïc J Blum
Aug 5, 2003·Journal of Molecular Recognition : JMR·Wlad Kusnezow, Jörg D Hoheisel
Oct 2, 2003·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·B Jahn-SchmidM W Mueller
Nov 5, 2003·Proteomics·Michael L Phelan, Steffen Nock
Nov 5, 2003·Proteomics·Markus F TemplinThomas O Joos
Nov 5, 2003·Proteomics·Seung-yong Seong, Cheol-young Choi
Nov 5, 2003·Proteomics·Barry SchweitzerMichael Snyder
Nov 11, 2003·Nature Biotechnology·Gregory A MichaudBarry I Schweitzer
Dec 23, 2003·Journal of Biomedicine & Biotechnology·Qingchai Xu, Kit S. Lam
Feb 28, 2004·Analytical Chemistry·Giovanna PirriLaura E Depero
Mar 17, 2004·Biomaterials·Yongseok JunX-Y Zhu
Mar 18, 2004·Bioconjugate Chemistry·Xavier DuburcqOleg Melnyk
Mar 18, 2004·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Rainer Bischoff, Theo M Luider
Mar 24, 2004·Current Opinion in Chemical Biology·Paul F Predki
May 15, 2004·Biosensors & Bioelectronics·Hsin-Yun Hsu, Yi-You Huang
Jul 3, 2004·Science·Niroshan RamachandranJoshua LaBaer
Jul 16, 2004·Analytical Chemistry·Heidelinde R C DietrichIan T Young
Jul 21, 2004·Journal of Immunological Methods·Virginia EspinaLance A Liotta
Aug 11, 2004·Analytical Biochemistry·Marina CretichMarcella Chiari
Sep 29, 2004·Current Opinion in Chemical Biology·Dal-Hee Min, Milan Mrksich
Oct 12, 2004·Journal of Proteome Research·D FinnskogG Marko-Varga
Oct 12, 2004·Journal of Proteome Research·M A ColemanP T Beernink

❮ Previous
Next ❯

Citations

Dec 13, 2012·Analytical and Bioanalytical Chemistry·Leticia FernándezIsabel Haro
Aug 20, 2011·Bioprocess and Biosystems Engineering·Gulay Bayramoglu, M Yakup Arica
Nov 26, 2013·Journal of Immunological Methods·Tinashe B RuwonaMansun Law
Nov 17, 2007·The Journal of Physical Chemistry. B·Jun FengB Montgomery Pettitt
Oct 31, 2006·Omics : a Journal of Integrative Biology·Adriana Aguilar-MahechaMark Basik
Oct 31, 2006·Omics : a Journal of Integrative Biology·Soon Jin OhJoon Won Park
Apr 21, 2009·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Candan Tamerler, Mehmet Sarikaya
Mar 24, 2011·Future Medicinal Chemistry·Hadar Benyamini, Assaf Friedler
Sep 28, 2010·The Journal of Chemical Physics·Shuai Wei, Thomas A Knotts
May 17, 2011·The Journal of Chemical Physics·Shuai Wei, Thomas A Knotts
Nov 5, 2013·The Review of Scientific Instruments·A P ReddingtonM S Ünlü
Sep 14, 2013·The Journal of Chemical Physics·Shuai Wei, Thomas A Knotts
Aug 12, 2014·The Journal of Chemical Physics·Brandon K Loong, Thomas A Knotts
Dec 31, 2015·Analytical and Bioanalytical Chemistry·Liu ShiEmmanuelle Laurenceau
Mar 17, 2010·Ultramicroscopy·So Yeon KimJunhong Min
Mar 10, 2009·Journal of Bioscience and Bioengineering·Naoki MatsumotoHiroyuki Honda
Aug 5, 2008·Biosensors & Bioelectronics·Peter Durand SkottrupAnnemarie Fejer Justesen
Mar 26, 2015·Nanomedicine : Nanotechnology, Biology, and Medicine·Kristina BrazhnikAlyona Sukhanova
Mar 2, 2011·Journal of Molecular Recognition : JMR·Giulio OlivieroPaolo Bergese
Jun 3, 2010·Biotechnology Journal·Palmiro PoltronieriYifen Wang
Sep 1, 2006·Clinica Chimica Acta; International Journal of Clinical Chemistry·José M González-BuitragoIsabel Lorenzo
Mar 11, 2008·Biophysical Journal·Thomas A KnottsJuan J de Pablo
Jan 16, 2008·Analytical Biochemistry·Ding WuStephen J Kron
Jul 2, 2011·Journal of Immunological Methods·C PereiraD A Bergstein
Aug 9, 2016·Journal of Virological Methods·Alexander G PoltavchenkoVadim N Gureyev

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Current Opinion in Biotechnology
Ulf ReimerJens Schneider-Mergener
Chembiochem : a European Journal of Chemical Biology
Mike SchutkowskiUlf Reimer
Current Opinion in Chemical Biology
Heng Zhu, Michael Snyder
© 2021 Meta ULC. All rights reserved