PMID: 11920674Mar 29, 2002Paper

Protein and surface effects on monocyte and macrophage adhesion, maturation, and survival

Journal of Biomedical Materials Research
Terry O Collier, J M Anderson

Abstract

Cell adhesion and maturation can be affected by the protein adsorption profile on the surface of an implanted biomaterial. In this study we have investigated how surface chemistry and adsorbed proteins can modulate monocyte and macrophage adhesion, IL-13-induced foreign-body giant cell formation, and apoptosis in vitro. Compared to a dimethylsilane-modified surface (DM), a surface modified with RGD peptides had no effect on adhesion density, foreign-body giant cell (FBGC) formation, or apoptosis in nondepleted serum conditions. The depletion of specific adhesive proteins affected adhesion, FBGC formation, and apo- ptosis. While the depletion of fibronectin and vitronectin had no overall effect compared to nondepleted serum conditions, the depletion of IgG from serum caused a significant decrease in initial adherent cell density [1000 +/- 200 compared to 2460 +/- 590 (p = 0.02)], a significant decrease in FBGC formation [2% compared to 17% (p = 0.02)], and a significant increase in the level of apoptosis [57% compared to 32% (p = 0.01)] on DM. The lowered initial adherent cell density on DM was not observed on the RGD surface, indicating that the RGD surface promotes increased initial adhesion. However, the RGD surface does not ...Continue Reading

References

Jul 15, 1977·International Journal of Cancer. Journal International Du Cancer·E Engvall, E Ruoslahti
Aug 2, 1990·Nature·T A Springer
Apr 1, 1990·Journal of Vascular Surgery·D A PankowskyJ M Anderson
Oct 1, 1985·Experimental Cell Research·E G HaymanE Ruoslahti
Oct 23, 1987·Science·E Ruoslahti, M D Pierschbacher
Jan 1, 1988·Biomaterials·N P ZiatsJ M Anderson
Aug 1, 1973·American Journal of Clinical Pathology·A D CramerR J Lukes
Jan 1, 1984·Biomaterials·J M Anderson, K M Miller
Jul 28, 1995·Biochimica Et Biophysica Acta·C RosalesR Juliano
Feb 1, 1995·Journal of Leukocyte Biology·C Rosales, R L Juliano
Jan 1, 1994·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·J M Cavaillon
Oct 11, 1994·Proceedings of the National Academy of Sciences of the United States of America·A K McNally, J M Anderson
Jun 1, 1994·Journal of Biomedical Materials Research·S I ErtelT A Horbett
Sep 1, 1996·Journal of Biomedical Materials Research·W J KaoJ M Anderson
May 30, 1997·Science·C S ChenD E Ingber
Apr 30, 1998·Current Opinion in Cell Biology·A HoweR L Juliano
Jul 24, 1998·Cellular and Molecular Life Sciences : CMLS·C G GahmbergT Pessa-Morikawa
Dec 19, 1998·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·K M DeFifeJ M Anderson
May 4, 1999·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·K M DeFifeJ M Anderson
Jun 5, 1999·Journal of Biomedical Materials Research·C R Jenney, J M Anderson
Aug 25, 1999·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·A Rezania, K E Healy
Oct 3, 1999·Microscopy Research and Technique·P DefilippiG Tarone
Oct 26, 1999·Cellular Signalling·G Berton, C A Lowell
Nov 7, 1999·Journal of Colloid and Interface Science·C E GiacomelliW Norde
Nov 24, 1999·Journal of Biomedical Materials Research·T O CollierK E Healy
Dec 22, 1999·Journal of Biomedical Materials Research·C R Jenney, J M Anderson
Mar 29, 2000·Journal of Biomedical Materials Research·C R Jenney, J M Anderson
Mar 31, 2000·Experimental Cell Research·S H Kaufmann, W C Earnshaw
Apr 25, 2000·Biochemical and Biophysical Research Communications·C A RichardD J Loegering
Apr 5, 2001·Journal of Biomedical Materials Research·W G BrodbeckJ M Anderson
Jun 28, 2001·Journal of Biomedical Materials Research·W J KaoJ A Hubbell
Sep 7, 2004·Journal of Materials Science. Materials in Medicine·J M AndersonC Jenney

❮ Previous
Next ❯

Citations

Jun 29, 2007·Journal of Materials Science. Materials in Medicine·A K Bajpai
Jul 15, 2011·Journal of Materials Science. Materials in Medicine·Inês C GonçalvesBuddy D Ratner
Jan 15, 2008·Langmuir : the ACS Journal of Surfaces and Colloids·Ashwin NairLiping Tang
Apr 18, 2012·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Scott R SchrickerBharat Bhushan
Oct 10, 2006·Journal of Biomaterials Science. Polymer Edition·Mutsumi Yoshida, Julia E Babensee
May 31, 2015·Advanced Drug Delivery Reviews·Siew-Min OngSiew-Cheng Wong
Jun 19, 2012·Acta Biomaterialia·Jaehyung Park, Julia E Babensee
Oct 17, 2007·The FEBS Journal·George S Wilson, Malika Ammam
Apr 22, 2011·Journal of Biomedical Materials Research. Part a·Rena M CorneliusJulia E Babensee
Jun 2, 2009·Journal of Biomedical Materials Research. Part a·Judite N BarbosaMário A Barbosa
Jun 26, 2012·Journal of Tissue Engineering and Regenerative Medicine·F BoccafoschiM Cannas
Jul 9, 2005·Biomaterials·Andrés J García
Aug 8, 2015·Biomacromolecules·Kai HuaNatalia Ferraz
Jul 17, 2004·Annual Review of Biomedical Engineering·Buddy D Ratner, Stephanie J Bryant
Feb 5, 2013·Acta Biomaterialia·M BinazadehL D Unsworth
Mar 5, 2016·Journal of Biomedical Materials Research. Part a·Hannah C Bygd, Kaitlin M Bratlie
Nov 7, 2016·Journal of Biomedical Science·G S SailajaH K Varma
Apr 23, 2017·Seminars in Immunology·Ashwin Nair, Liping Tang
Jan 26, 2007·Journal of Biomedical Materials Research. Part a·Loren A MathesonRosalind S Labow
Apr 24, 2008·Journal of Biomedical Materials Research. Part a·Analiz RodriguezJames M Anderson
Aug 24, 2017·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Yoon Ah ParkYoung Joon Seo
Nov 4, 2009·Journal of Diabetes Science and Technology·Amanda W Bridges, Andrés J García
Mar 19, 2016·Advanced Healthcare Materials·Leila NayyerAlexander M Seifalian
Feb 7, 2021·Materials Science & Engineering. C, Materials for Biological Applications·K PrzykazaR Mroczka
May 22, 2021·Frontiers in Bioengineering and Biotechnology·Fu WeiQuanyi Guo
Dec 10, 2018·ACS Biomaterials Science & Engineering·Nils HildebrandLucio Colombi Ciacchi
Sep 21, 2007·The Journal of Physical Chemistry. B·Sabrina S JedlickaDmitry Y Zemlyanov
Oct 6, 2021·Journal of Biomaterials Applications·Tijana Lužajić BožinovskiDanica Marković

❮ Previous
Next ❯

Related Concepts

Related Feeds

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.