Protein-based phylogenies support a chimeric origin for the eukaryotic genome

Molecular Biology and Evolution
G B Golding, R S Gupta

Abstract

The phylogenetic position of the archaebacteria and the place of eukaryotes in the history of life remain a question of debate. Recent studies based on some protein-sequence data have obtained unusual phylogenies for these organisms. We therefore collected the protein sequences that were available with representatives from each of the major forms of life: the gram-negative bacteria, gram-positive bacteria, archaebacteria, and eukaryotes. Monophyletic, unrooted phylogenies based on these sequence data show that seven of 24 proteins yield a significant gram-positive-archaebacteria clade/gram-negative-eukaryotic clade. The phylogenies for these seven proteins cannot be explained by the traditional three-way split of the eukaryotes, archaebacteria, and eubacteria. Nine of the 24 proteins yield the traditional gram-positive-gram-negative clade/archaebacteria-eukaryotic clade. The remaining eight proteins give phylogenies that cannot be statistically distinguished. These results support the hypothesis of a chimeric origin for the eukaryotic cell nucleus formed from the fusion of an archaebacteria and a gram-negative bacteria.

Citations

Dec 1, 1996·Journal of Molecular Evolution·T Cavalier-Smith, E E Chao
Dec 13, 2006·Journal of Molecular Evolution·Jie Luo, Benjamin D Hall
Jun 7, 2005·Bio Systems·Valery KirzhnerEviatar Nevo
Aug 15, 2002·Trends in Genetics : TIG·Yuri I WolfEugene V Koonin
Dec 1, 1996·Trends in Ecology & Evolution·J R Brown
Dec 1, 1998·Trends in Ecology & Evolution·L A Katz
Aug 20, 1996·Proceedings of the National Academy of Sciences of the United States of America·W F Doolittle
Feb 6, 1996·Proceedings of the National Academy of Sciences of the United States of America·L Margulis
Mar 19, 1996·Proceedings of the National Academy of Sciences of the United States of America·G BurgerM W Gray
May 30, 1998·Proceedings of the National Academy of Sciences of the United States of America·M C RiveraJ A Lake
Oct 30, 2009·Proceedings. Biological Sciences·Luis Boto
Dec 5, 1997·Proceedings of the National Academy of Sciences of the United States of America·W F Doolittle
Aug 30, 2006·Proceedings of the National Academy of Sciences of the United States of America·Lynn MargulisJohn Hall
Jun 22, 2000·Proceedings of the National Academy of Sciences of the United States of America·L MargulisR Guerrero
Dec 16, 1997·Proceedings of the National Academy of Sciences of the United States of America·D F FengR F Doolittle
Oct 21, 1999·The American Naturalist·L A Katz
Jun 6, 2009·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Yaacov Davidov, Edouard Jurkevitch
Mar 16, 2000·Journal of Theoretical Biology·M Di Giulio
Feb 26, 2000·Annual Review of Genetics·B F LangG Burger
Sep 12, 1998·Theoretical Population Biology·R S Gupta
Jun 1, 1996·Current Biology : CB·B Golding
Oct 3, 2001·BMC Evolutionary Biology·S B HedgesH Watanabe
Sep 7, 2001·Annual Review of Microbiology·E V KooninL Aravind
Apr 27, 2016·Environmental Microbiology·Laura VillanuevaJaap S Sinninghe Damsté
Jan 1, 1996·Annual Review of Genetics·M Nei
Feb 3, 1999·Annual Review of Genetics·S Casjens
Dec 9, 2000·Molecular Biology and Evolution·K K KoretkeJ R Brown
Jun 30, 2001·Nature Genetics·J R BrownM J Stanhope
Feb 1, 2003·Nature Reviews. Genetics·James R Brown
Jun 2, 2010·EMBO Reports·Antony M Dean
Mar 7, 2020·Genome Biology and Evolution·Julia Brueckner, William F Martin
Feb 23, 1999·Microbial & Comparative Genomics·M A Ragan, T Gaasterland

❮ Previous
Next ❯

Related Concepts

Related Feeds

Archaeogenetics

Recent advances in genomic sequencing has led to the discovery of new strains of Archaea and shed light on their evolutionary history. Discover the latest research on Archaeogenetics here.

Related Papers

Trends in Biochemical Sciences
R S Gupta, G B Golding
Proceedings of the National Academy of Sciences of the United States of America
D F FengR F Doolittle
Current Opinion in Genetics & Development
W Zillig
© 2021 Meta ULC. All rights reserved