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"Protein cancers" hypothesis for neurodegenerative diseases

Rinshō shinkeigaku = Clinical neurology

Jan 27, 2012

Masato Hasegawa

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PubMed

Abstract

Intracellular filamentous inclusions composed of amyloid-like proteins are common neuropathological features of many neurodegenerative disorders. Although the extent of the abnormal protein pathologies is closely correlated with the disease progression, little attention has been given t...read more

Mentioned in this Paper

TARDBP gene
SNCA gene
Abnormal protein
APP protein, human
Ubiquitin
Protoplasm
Degenerative Diseases, Spinal Cord
Neurodegenerative Disorders Pathway
Neoplasms
Cancer Progression
Paper Details
References
  • References8
  • Citations1
1
  • References8
  • Citations1
1

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Related Papers

Rinshō shinkeigaku = Clinical neurology

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"Protein cancers" hypothesis for neurodegenerative diseases

Rinshō shinkeigaku = Clinical neurology

Jan 27, 2012

Masato Hasegawa

PMID: 22277495

DOI: 10.5692/clinicalneurol.51.1101

Abstract

Intracellular filamentous inclusions composed of amyloid-like proteins are common neuropathological features of many neurodegenerative disorders. Although the extent of the abnormal protein pathologies is closely correlated with the disease progression, little attention has been given t...read more

Mentioned in this Paper

TARDBP gene
SNCA gene
Abnormal protein
APP protein, human
Ubiquitin
Protoplasm
Degenerative Diseases, Spinal Cord
Neurodegenerative Disorders Pathway
Neoplasms
Cancer Progression

Feeds With Similar Papers

Synucleinopathies

Synucleinopathies are neurodegenerative diseases characterized by accumulation of alpha-synuclein protein aggregates in neurons and glial cells. Discover the latest research on synucleinopathies here.

Alpha-Synuclein Aggregation (MDS)

Alpha-synucleins are small proteins that are believed to restrict the mobility of synpatic vesicles and inhibit neurotransmitter release. Aggregation of these proteins have been linked to several types of neurodegenerative diseases including dementia with Lewy bodies and Parkinson's disease. Here is the latest research on α-synuclein aggregation.

Related Papers

Rinshō shinkeigaku = Clinical neurology

Molecular dissection of TDP-43 in ALS and FTLD

Rinshō shinkeigaku = Clinical neurologySeptember 17, 2011
Masato HasegawaHaruhiko Akiyama
Rinshō shinkeigaku = Clinical neurology

Seed, aggregation and propagation of abnormal proteins could explain neurodegeneration?

Rinshō shinkeigaku = Clinical neurologyJanuary 27, 2012
Shigeo Murayama
Paper Details
References
  • References8
  • Citations1
1
  • References8
  • Citations1
1

Download from

Publisher
PubMed
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