PMID: 16523378Mar 9, 2006Paper

Protein expression -- CHI's Ninth Annual Conference

IDrugs : the Investigational Drugs Journal
Ingrid Marchal-Gerez

Abstract

This 2-day meeting, which was part of the annual PepTalk event, was well attended, and had a strong representation from major pharmaceutical companies and newer biotechnology companies. Attendees were primarily concerned with the expression of soluble proteins for structural studies and, to a lesser extent, with industrial production of therapeutic proteins. New tools were presented by suppliers in order to address the industry's demand for flexible and reliable technologies for screening, optimization and scale-up. Strategies to overcome the primary bottlenecks and achieve expression in high quantity and quality were also disclosed.

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