PMID: 9439145Jun 1, 1997Paper

Protein intake and the nutritional status in patients with pre-dialysis chronic renal failure on unrestricted diet

The Korean Journal of Internal Medicine
J S ParkC D Hong

Abstract

Malnutrition is known to be highly associated with morbidity and mortality in dialysis patients. Malnutrition may begin to develop in patients with chronic renal failure(CRF) before they need dialysis. In this study, the nutritional status of patients with moderate to severe CRF on unrestricted diet was evaluated. We measured dietary protein intake (DPI, g/kg/day) in 64 patients with CRF and 42 normal controls(N). Nutritional indices such as serum albumin(SA, g/dl), transferrin(TF, mg/dl), prealbumin(PA, mg/dl) and insulin-like growth factor-1(IGF-1, ng/ml) were measured to evaluate the visceral proteins, and creatinine-height index(C-H, g/d/m) to evaluate the somatic proteins. Mean DPI was 0.80 +/- 0.27(S.D) in CRF and 1.07 +/- 0.30 in N(p < 0.0001). DPI was lower than 0.6 in 15 CRF patients(23%). Serum albumin, transferrin and C-H were significantly lower in CRF patients than in N(p < 0.01). In patients with CRF, nutritional indices were significantly worse with lower DPI(< 0.6 g/kg/d, n = 15) than higher DPI(> 0.6 g/kg/d, n = 49)(SA 2.9 +/- 0.7 vs. 3.6 +/- 0.8, p < 0.005; TF 147 (134-179) vs. 220(182-264), p < 0.0005; PA 24 +/- 8 vs. 32 +/- 9, p < 0.001; IGF-1 123 (66-261) vs. 226(140-344), p < 0.05; C-H 0.52 +/- 0.15 vs. 0....Continue Reading

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Citations

May 26, 2001·Annual Review of Nutrition·R Mehrotra, J D Kopple
Oct 24, 2007·Journal of the Neurological Sciences·Jong Seok Bae, Sung Sik Park
Nov 21, 2012·Journal of Korean Medical Science·Seok Hui KangJun Young Do
Oct 31, 2012·Seminars in Dialysis·Jochen G RaimannGarry Handelman
Jul 19, 2013·Seminars in Dialysis·Catherine M ClaseRachel M Holden
Jan 7, 2004·Advances in Renal Replacement Therapy·Rajnish Mehrotra, Joel D Kopple

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