Protein intake in early childhood and cardiometabolic health at school age: the Generation R Study

European Journal of Nutrition
Trudy VoortmanOscar H Franco

Abstract

High protein intake in infancy has been linked to obesity. We aimed to examine the associations of protein intake in early childhood with cardiovascular and metabolic outcomes at school age. This study was performed in 2965 children participating in a population-based prospective cohort study. Protein intake at 1 year was assessed with a food frequency questionnaire and was adjusted for energy intake. At the children's age of 6 years, we measured their body fat percentage (BF%), blood pressure (BP), and insulin, HDL cholesterol, and triglyceride serum levels. These measures were incorporated into a cardiometabolic risk factor score, using age- and sex-specific SD scores. In covariate-adjusted models, higher protein intake was associated with a higher BF%, lower diastolic BP, and lower triglyceride levels. We observed a significant interaction of protein intake with child sex on metabolic outcomes. Stratified analyses showed that protein intake was positively associated with BF% [0.07 SD (95 % CI 0.02; 0.13) per 10 g/day] and insulin levels in girls, but not in boys. In boys, but not in girls, higher protein intake was associated with lower triglyceride levels [-0.12 SD (95 % CI -0.20; -0.04) per 10 g/day] and a lower cardiometa...Continue Reading

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Feb 16, 2018·The Cochrane Database of Systematic Reviews·Celeste E NaudeAnel Schoonees
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Methods Mentioned

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SPSS Statistics
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