Protein-losing enteropathy due to intestinal lymphangiectasia accompanied by mesenteric lymph node fibrosis

Pathology International
S NakanoS Miura

Abstract

An autopsy case of a 74-year-old man suffering from edema in the legs and diagnosed as protein-losing enteropathy due to intestinal lymphangiectasia is presented. He underwent a radical operation and radiotherapy for esophageal carcinoma at age 65 years and the onset of protein-losing enteropathy was at age 70. Postmortem examination disclosed widespread abnormalities of the duodenal and small intestinal lymphatics and mesenteric lymph node fibrosis. The mucosal lymphatic capillaries were markedly dilated. In the submucosal and serosal layers, the lymphatic vessels showed marked dilatation in some areas and fibrous occlusion with very thick muscle layers in others. All these lymphatic changes were presumed to be attributable to a reactive process secondary to lymph congestion, which it is suggested, was caused by the mesenteric lymph node fibrosis.

References

Oct 1, 1989·Journal of Pediatric Gastroenterology and Nutrition·A G ThomasV Miller
Aug 1, 1987·Digestive Diseases and Sciences·S S RaoC D Holdsworth
Mar 1, 1966·Gastroenterology·T A Waldmann
Mar 21, 1957·The New England Journal of Medicine·A H BAGGENSTOSS, J CAIN

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Citations

Sep 23, 2014·Seminars in Pediatric Surgery·Ravindhra G ElluruHoracio M Padua

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