PMID: 8971890Dec 1, 1996Paper

Protein losses in children on continuous cycler peritoneal dialysis

Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
A Quan, M Baum

Abstract

Peritoneal dialysis can result in significant protein losses through the dialysate effluent. Although protein loss in chronic ambulatory peritoneal dialysis has been examined, it has not been extensively studied in patients on continuous cycler peritoneal dialysis. Such losses can contribute to protein calorie malnutrition, especially in infants and children, many of whom are on continuous cycler peritoneal dialysis. We measured protein loss during continuous cycler peritoneal dialysis in patients ranging in age from 2 months to 18 years. There was an inverse correlation between body surface area and peritoneal protein loss, expressed both as milligrams of protein per kilogram body weight per day (P < 0.0001) and as milligrams of protein per meter square body surface area per day (P < 0.05). Peritoneal fluid protein losses in patients greater than 50 kg were similar to those previously reported in adults treated with chronic ambulatory peritoneal dialysis. In contrast, infants had nearly twofold greater peritoneal protein losses per meter square body surface area than older children weighing more than 50 kg. Such protein losses in infants impair normal growth and may contribute to permanent loss of growth potential. Infants on ...Continue Reading

Citations

May 8, 2000·Indian Journal of Pediatrics·A Kalia
Jun 15, 2006·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Sashikala KopanatiAlbert Quan
Jan 12, 2007·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Lesley Rees, Vanessa Shaw
Feb 7, 2008·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Fabio Paglialonga, Alberto Edefonti
Oct 12, 2012·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Aleksandra M ZurowskaUNKNOWN European Paediatric Dialysis Working Group
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Sep 6, 2013·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Antonio MastrangeloAlberto Edefonti
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Jul 6, 2018·Frontiers in Pediatrics·Franca M Iorember
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