Protein nanopatterns for improved immunodetection sensitivity

Analytical Chemistry
A ValsesiaF Rossi

Abstract

In this work, we clearly demonstrate the capability of protein nanopatterns of improving the quality factors of immunosensing devices, such as lowering of the limit of detection and increase of sensitivity. This beneficial effect is obtained by the formation on the sensor's surface of bioadhesive domains of nanometric dimensions in a nonadhesive matrix by means of colloidal lithography.

References

Feb 1, 1996·Current Opinion in Biotechnology·V Hlady, J Buijs
Nov 24, 2001·Clinica Chimica Acta; International Journal of Clinical Chemistry·P B LuppaD W Chan
May 9, 2002·Journal of Biotechnology·Shaojun Dong, Xu Chen
Nov 27, 2004·The Analyst·Damien W M Arrigan
Feb 8, 2006·Langmuir : the ACS Journal of Surfaces and Colloids·Andrea ValsesiaFrançois Rossi
Jun 15, 2006·Nano Letters·H AgheliD S Sutherland
Jan 29, 2008·Analytical Chemistry·A ValsesiaF Rossi

❮ Previous
Next ❯

Citations

Aug 13, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Zachary R TaylorDavid W Schmidtke
Nov 5, 2013·The Journal of Physical Chemistry. a·A MalainouA Tserepi
Aug 13, 2011·Current Opinion in Chemical Biology·Peter KingshottHans J Griesser
Sep 20, 2011·IEEE Transactions on Nanobioscience·Maria SundhDuncan S Sutherland
Jun 5, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Zachary R TaylorDavid W Schmidtke
Dec 16, 2017·Nanotechnology·Xiangping Li, Andreas Manz
Apr 17, 2018·Langmuir : the ACS Journal of Surfaces and Colloids·Lijun T RajuSaptarshi Basu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antibody Specificity

Antibodies produced by B cells are highly specific for antigen as a result of random gene recombination and somatic hypermutation and affinity maturation. As the main effector of the humoral immune system, antibodies can neutralize foreign cells. Find the latest research on antibody specificity here.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America
Olivia du RoureBenoit Ladoux
Nature Reviews. Drug Discovery
David SchramaJürgen C Becker
Journal of Cancer Research and Therapeutics
Shantesh Hede, Nagraj Huilgol
© 2022 Meta ULC. All rights reserved