Abstract
Protein patterning on solid surfaces is a topic of significant importance in the fields of biosensors, diagnostic assays, cell adhesion technologies, and biochip microarrays. In this letter, we have established a novel, rapid method for the fabrication of a "protein recording material", which enables us to spatiotemporally regulate the recording, reading, and erasing of a fluorescent protein array as information by a photochemical technique. A photolinker that we synthesized here was used to control the protein array spatiotemporally. The recording process was almost completed after 1 min of photoirradiation to read a clear pattern consisting of a specific protein-ligand complex with high spatiotemporal resolution. The erasing of the protein array was then achieved by photoirradiation onto the entire patterned surface.
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May 28, 2011·Advanced Materials·Melanie WirknerAránzazu del Campo
Dec 12, 2012·Macromolecular Rapid Communications·Jiaxi CuiAranzazu del Campo
Jun 12, 2013·Chemical Communications : Chem Comm·Kenji UsuiHisakazu Mihara
May 30, 2008·Langmuir : the ACS Journal of Surfaces and Colloids·Koji NakayamaTetsuro Majima