Protein recycling is a major component of post-irradiation recovery in Deinococcus radiodurans strain R1

Biochemical and Biophysical Research Communications
Bhakti JoshiShree K Apte

Abstract

Exposure to 6kGy dose of (60)Co gamma-rays resulted in immediate growth arrest, followed by complete recovery of Deinococcus radiodurans strain R1 cells. Selective degradation and resynthesis of several predicted highly expressed proteins (including major chaperones, key TCA cycle enzymes, and few stress proteins) and several hypothetical proteins marked the lag period, preceding resumption of growth. A major exercise in protein recycling appears to be an integral component of post-irradiation recovery in D. radiodurans and complements the extensive DNA repair, characteristic of this extremely radioresistant bacterium.

References

Jan 1, 1987·Journal of Bacteriology·K H Paek, G C Walker
Jul 6, 1973·Nature·A Travers
Jan 1, 1974·Journal of Supramolecular Structure·C P Georgopoulos, H Eisen
Aug 1, 1996·Journal of Bacteriology·P GraumannM A Marahiel
May 1, 1996·Radiation and Environmental Biophysics·A TanakaH Watanabe
Jan 1, 1997·Annual Review of Microbiology·J R Battista
Feb 18, 1999·Molecular and Cellular Biology·S P GygiR Aebersold
Apr 29, 2000·Cell·B BukauE A Craig
Apr 11, 2001·Proceedings of the National Academy of Sciences of the United States of America·S Karlin, J Mrazek
Aug 15, 2002·Proceedings of the National Academy of Sciences of the United States of America·Mary S LiptonRichard D Smith
Oct 26, 2002·Journal of Bacteriology·Ashlee M EarlJohn R Battista
Dec 18, 2002·Journal of Bacteriology·Shery VargheseJames A Imlay
Jan 11, 2003·Science·Smadar Levin-ZaidmanAbraham Minsky
Mar 26, 2003·Proceedings of the National Academy of Sciences of the United States of America·Yongqing LiuMichael J Daly
Jun 14, 2003·Biochemical and Biophysical Research Communications·Yuejin HuaBinghui Shen

❮ Previous
Next ❯

Citations

Aug 9, 2005·Biochemical and Biophysical Research Communications·Bhaskar Jyoti PrasadDileep N Deobagkar
Oct 13, 2011·Molecular & Cellular Proteomics : MCP·Bhakti Basu, Shree Kumar Apte
Oct 24, 2006·Applied and Environmental Microbiology·Deepti AppukuttanShree Kumar Apte
Mar 5, 2011·Microbiology and Molecular Biology Reviews : MMBR·Dea Slade, Miroslav Radman
Apr 3, 2016·Mutation Research. Reviews in Mutation Research·Athanasia PavlopoulouAlexandros G Georgakilas
Jul 2, 2008·Biochimica Et Biophysica Acta·Bhakti Basu, Shree Kumar Apte
Aug 7, 2018·Journal of Basic Microbiology·Harinder Singh
Jun 24, 2008·Critical Reviews in Biochemistry and Molecular Biology·Melanie BlasiusUlrich Hübscher
Nov 17, 2015·Biochemistry. Biokhimii︠a︡·A A Agapov, A V Kulbachinskiy
Sep 30, 2020·Journal of Biomolecular Structure & Dynamics·Dhirendra K SharmaYogendra S Rajpurohit
Jan 1, 2009·Genomics Insights·Na GaoHong-Yu Zhang
Oct 27, 2018·The Protein Journal·Harinder Singh, Shree Kumar Apte

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.