Protein splicing of SufB is crucial for the functionality of the Mycobacterium tuberculosis SUF machinery.

Journal of Bacteriology
Gaëlle HuetIsabelle Saves

Abstract

The SufBCD complex is an essential component of the SUF machinery of [Fe-S] cluster biogenesis in many organisms. We show here that in Mycobacterium tuberculosis the formation of this complex is dependent on the protein splicing of SufB, suggesting that this process is a potential new target for antituberculous drugs.

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Citations

May 17, 2011·PloS One·Ruma BanerjeeRajendra Joshi
Aug 5, 2015·Proceedings of the National Academy of Sciences of the United States of America·Natalya I TopilinaMarlene Belfort
Feb 7, 2008·Biochimica Et Biophysica Acta·Chris D den Hengst, Mark J Buttner
Dec 3, 2014·Biochimica Et Biophysica Acta·F Wayne Outten
May 11, 2013·Biochimica Et Biophysica Acta·Béatrice RocheFrédéric Barras
Jan 10, 2013·Biochimica Et Biophysica Acta·Béatrice RocheFrédéric Barras

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