PMID: 7536565Nov 1, 1994Paper

Protein starvation and the trophic barrier functions of the enzymatic and transport systems of the digestive and nondigestive organs in adult and growing rats

Fiziologicheskiĭ zhurnal imeni I.M. Sechenova
N M TimofeevaL A Gordova

Abstract

A reduced activity of cytosol dipeptidases was revealed both in epithelial and subepithelial layers of the small intestine against the background of protein deprivation in adult and maturing rats. The latters' enzyme systems of the small intestine and kidneys' layers proved to be particularly sensitive to protein deprivation. The disturbance of the digestive-barrier functions provides favourable conditions for penetration of foreign protein and peptide substances into the organism's inner milieu which can be dangerous for a maturing organism.

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