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Protein structure determination by combining sparse NMR data with evolutionary couplings

Nature Methods

Jun 30, 2015

Yuefeng TangGaetano T Montelione

Abstract

Accurate determination of protein structure by NMR spectroscopy is challenging for larger proteins, for which experimental data are often incomplete and ambiguous. Evolutionary sequence information together with advances in maximum entropy statistical methods provide a rich complementar...read more

Mentioned in this Paper

In Vivo NMR Spectroscopy
Size
Gene Products, Protein
Determination Aspects
Crystallography, X-Ray
Hydrodynamics
Viral Structural Proteins
P21 N-Ras Protein
Protein Conformation
Structure
5
1
115
Paper Details
References
  • References56
  • Citations18
12345...
  • References56
  • Citations18
12

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Protein structure determination by combining sparse NMR data with evolutionary couplings

Nature Methods

Jun 30, 2015

Yuefeng TangGaetano T Montelione

PMID: 26121406

DOI: 10.1038/nmeth.3455

Abstract

Accurate determination of protein structure by NMR spectroscopy is challenging for larger proteins, for which experimental data are often incomplete and ambiguous. Evolutionary sequence information together with advances in maximum entropy statistical methods provide a rich complementar...read more

Mentioned in this Paper

In Vivo NMR Spectroscopy
Size
Gene Products, Protein
Determination Aspects
Crystallography, X-Ray
Hydrodynamics
Viral Structural Proteins
P21 N-Ras Protein
Protein Conformation
Structure
5
1
115

Similar Papers Found In These Feeds

Structural Biology: Biophysics

Structural Biology: Biophysics describes the study of structural biology using various biophysical techiniques such as imaging, computational modeling, etc. Discover the latest research on structrual biology here.

Viral Protein Structures

Viral proteins are used for assembly and for assisting in infection and replication in the host. The structure of these viral proteins depends on their function. Capsid proteins surround the virus and can take on different forms depending the mechanism of entry. Here is the latest research on viral protein structures.

Related Papers

Angewandte Chemie

De novo structure determination from residual dipolar couplings by NMR spectroscopy

Angewandte ChemieDecember 20, 2002
Bernd Simon, Michael Sattler
Paper Details
References
  • References56
  • Citations18
12345...
  • References56
  • Citations18
12
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