PMID: 5914763Oct 14, 1966

Protein synthesis by heart muscle ribosomes: an effect of insulin independent of substrate transport

W S Stirewalt, I G WOOL


Ribosomes from heart muscle of diabetic animals perfused for 15 minutes with insulin, but without added substrate, were more active in the catalysis of protein synthesis than were ribosomes from hearts perfused without insulin. This effect of insulin on the efficiency of protein synthesis seems not to result from transport of some critical substrate into muscle, nor is the effect on ribosomes mediated by a product of a tissue other than muscle.


Aug 1, 1969·The Journal of Experimental Zoology·H L HosickH A Bern
Jun 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·W S StirewaltP Cavicchi
Dec 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·I G WOOL, K Kurihara
Sep 1, 1970·Archives of Biochemistry and Biophysics·S Goldstein, W J Reddy
Nov 1, 1982·Indian Journal of Pediatrics·K S ReddyM L Bhatia
Feb 24, 1971·Nature: New Biology·T EkrenP O Seglen
Dec 28, 2017·Wiley Interdisciplinary Reviews. RNA·Curtis A Nutter, Muge N Kuyumcu-Martinez

Related Concepts

Diabetes Mellitus
Protein Biosynthesis

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