PMID: 7544443DOI: 10.1038/376737a0Aug 31, 1995Paper
Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions
Nature
S LevJ Schlessinger
Abstract
The protein tyrosine kinase PYK2, which is highly expressed in the central nervous system, is rapidly phosphorylated on tyrosine residues in response to various stimuli that elevate the intracellular calcium concentration, as well as by protein kinase C activation. Activation of PYK2 leads to modulation of ion channel function and activation of the MAP kinase signalling pathway. PYK2 activation may provide a mechanism for a variety of short- and long-term calcium-dependent signalling events in the nervous system.
References
Apr 1, 1979·Cell·M WiglerR Axel
Mar 20, 1992·Cell·S M ThomasJ S Brugge
Mar 20, 1992·Cell·K W WoodJ Blenis
Aug 7, 1992·Cell·E J LowensteinJ Schlessinger
Sep 1, 1992·Neuron·J Schlessinger, A Ullrich
Sep 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·W R HuckleH S Earp
Dec 17, 1992·Nature·M Rozakis-AdcockT Pawson
Jun 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·M D SchallerJ T Parsons
Oct 10, 1991·Nature·T J O'DellS G Grant
Nov 1, 1990·Neuron·R L Huganir, P Greengard
Feb 28, 1991·Nature·J A WagnerP Gardner
Jun 1, 1991·Neuron·B G WallaceR L Huganir
Sep 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·M PaulmichlD E Clapham
Dec 10, 1991·Biochimica Et Biophysica Acta·P Angel, M Karin
Jun 1, 1991·Current Opinion in Neurobiology·K R WagnerR L Huganir
Apr 5, 1991·Cell·R KleinM Barbacid
Jul 4, 1991·Nature·K G Chandy
Jan 1, 1988·Annual Review of Immunology·D Proud, A P Kaplan
Jul 1, 1988·Science·S K HanksT Hunter
May 19, 1994·Nature·Y T Wang, M W Salter
Aug 1, 1994·Molecular and Cellular Biology·A G BatzerJ Schlessinger
Apr 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·H ReppF Dreyer
Jan 27, 1995·Cell·C J Marshall
Jan 27, 1995·Cell·C S Hill, R Treisman
Jan 27, 1995·Cell·D E Clapham
Jan 1, 1994·Annual Review of Cell Biology·P van der GeerR A Lindberg
Mar 1, 1994·Journal of Neurobiology·A GhoshM E Greenberg
Dec 1, 1994·Molecular and Cellular Biology·R R MattinglyI G Macara
Dec 1, 1994·Neuron·M CovarrubiasT B Vyas
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
Dec 22, 1994·Nature·D D SchlaepferP van der Geer
Jun 1, 1994·Neuron·L B RosenM E Greenberg
Mar 1, 1994·Neuron·R M StephensD R Kaplan
Feb 1, 1994·Trends in Biochemical Sciences·L V Dekker, P J Parker
Dec 17, 1993·Cell·X Y HuangE G Peralta
Jan 28, 1993·Nature·M J Berridge
The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain
Apr 23, 1993·Cell·R MaraisR Treisman
Sep 10, 1993·Science·M LiW A Catterall
May 6, 1993·Nature·N LiJ Schlessinger
May 27, 1993·Nature·E ManserL Lim
Jul 1, 1993·Current Biology : CB·T Pawson, J Schlessingert
❮ Previous
Next ❯
Citations
Oct 8, 1997·The Prostate·R N SkrymaB Dufy
May 8, 1998·Journal of Cellular Physiology·O MelienT Christoffersen
Feb 27, 1999·Journal of Cellular Physiology·M O De NichiloK M Yamada
May 8, 2000·Journal of Cellular Physiology·M R SayedV Duronio
Dec 8, 1998·European Journal of Immunology·I SheflerR Sagi-Eisenberg
Dec 8, 1998·European Journal of Immunology·G A van SeventerJ M van Seventer
Nov 1, 2000·Cell Motility and the Cytoskeleton·L T Duong, G A Rodan
Jan 1, 1997·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·M D Sjaastad, W J Nelson
May 15, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·H MitsuiY Takuwa
Jan 12, 2002·Journal of Cellular Biochemistry·Shyamali RoySteven K Hanks
Jan 29, 2002·Journal of Neuroscience Research·Aeneas C MurnaneCharles H Keith
Oct 12, 2000·Cell Biology International·M S Ridyard, E J Sanders
Jul 14, 1998·Journal of Biomedical Science·S D Lin, M J Fann
Jul 14, 1998·Journal of Biomedical Science·C M ChouC J Huang
Jul 14, 1999·Cell Biochemistry and Biophysics·I Dikic, A Blaukat
Dec 15, 2005·Archives of Pharmacal Research·Jin Hyoung Kim, Hwa-Jung Kim
Jun 6, 2007·Pflügers Archiv : European journal of physiology·Konstantin HolzapfelFranz-Xaver Beck
Dec 17, 2009·Pflügers Archiv : European journal of physiology·Ingrid Fleming
Aug 5, 2010·Pflügers Archiv : European journal of physiology·Martin TresguerresLonny R Levin
Dec 2, 2009·Protoplasma·Stefan BaumeisterKlaus Lingelbach
Oct 31, 2007·Journal of Bone and Mineral Metabolism·Ichiro NakamuraGideon A Rodan
May 21, 2013·Molecules and Cells·Ssang-Taek Steve Lim
Apr 25, 2006·Modern Rheumatology·Tsuyoshi MiyazakiRoland Baron
Mar 10, 2010·Apoptosis : an International Journal on Programmed Cell Death·Yan Wang, Zheng-Hong Qin
Feb 6, 2008·Journal of Biomedical Science·Jwu-Lai YehJiunn-Ren Wu
Nov 21, 2008·Medical Oncology·Lei CaiXiaowu Li
Feb 2, 2008·Molecular Biotechnology·Louis M Luttrell
May 24, 1996·Chemistry and Physics of Lipids·V NatarajanS Vepa
Aug 1, 1996·Trends in Genetics : TIG·G S Barsh
Jan 1, 1996·Peptides·A TallettT Sethi
May 6, 1996·Biochimica Et Biophysica Acta·P Light
Jun 7, 1996·Biochimica Et Biophysica Acta·R K Malik, J T Parsons
Apr 1, 1996·Trends in Cardiovascular Medicine·P H Sugden, M A Bogoyevitch
Jan 27, 2004·Biochemical and Biophysical Research Communications·Yasuhiro TsunodaFumihiko Nozu
Feb 24, 2005·Brain Research·In Koo HwangMoo Ho Won
Oct 16, 2003·Brain Research. Molecular Brain Research·Akihiko KatoHiroyuki Sugiyama
Jan 27, 2004·Brain Research. Molecular Brain Research·Vardit RubovitchYosef Sarne
Jan 21, 2004·Neuroscience Letters·Jun GuoGuangyi Zhang
Mar 31, 2004·Neuroscience·S L HabernyK D Carr
Dec 23, 2003·Progress in Neurobiology·Thomas Arendt
May 27, 2005·Steroids·L W Kline, E Karpinski
Jun 8, 2002·Archives of Biochemistry and Biophysics·Tonous N Silfani, Ernest J Freeman
Jun 21, 2002·Biochemical and Biophysical Research Communications·Rosemary J KeoghCaroline P D Wheeler-Jones
May 3, 2003·Biochemical and Biophysical Research Communications·Ranjinder S SidhuRajinder P Bhullar
Jul 4, 2001·Biochemical Pharmacology·E R GrantZ Zhong
Oct 18, 2003·Biochemical Pharmacology·Frederic CoussinGraeme F Nixon
Oct 17, 1998·Biochemical Pharmacology·M W Salter
Feb 5, 1999·Biochemical Pharmacology·L J YangJ R Williamson
May 31, 2001·Brain Research·J S WonH W Suh
May 13, 1999·Brain Research·M RochaR Linden
❮ Previous
Next ❯
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