Proteinuria in preeclampsia: Not essential to diagnosis but related to disease severity and fetal outcomes

Pregnancy Hypertension
Xin DongQ Chen

Abstract

Preeclampsia is a leading cause of maternal and perinatal morbidity and mortality globally and proteinuria can be one of the cardinal features of this disease. However, studies about the association of the amount of proteinuria and the severity of preeclampsia, and perinatal outcomes are limited. Data on 239 women with preeclampsia were retrospectively collected from a university teaching hospital from September 2011 to June 2013 and analysed. Data included all clinical parameters and proteinuria in a 24h urine collection. In cases of severe preeclampsia, significantly fewer patients had proteinuria levels <0.3g/L in comparison to any of the other groups with proteinuria >0.3g/L, but there was no difference in cases of severe preeclampsia when proteinuria levels were >0.3g/L. Furthermore, when proteinuria levels were >0.3g/L, the frequency of severe preeclampsia in each group was significantly higher than the frequency of mild pre-eclampsia cases. Time of onset was significantly earlier in patients with proteinuria >3g/L in a 24h urine collection, but time between the onset of preeclampsia and delivery was not correlated with the amount of proteinuria. The birth weight was significantly lower in patients with proteinuria >3g/L....Continue Reading

Citations

Apr 4, 2019·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Atakan TanacanMehmet Sinan Beksac
Jan 16, 2020·Bulletin of Experimental Biology and Medicine·N V NizyaevaA I Shchegolev
Mar 5, 2020·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Johan Frangky SelannoEddy Hartono
Apr 30, 2020·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Dan LiuQi Chen
Feb 11, 2020·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Şafak Yılmaz BaranErhan Şimşek
Mar 3, 2020·Frontiers in Physiology·Nozha RaguemaMariane Bertagnolli
Oct 28, 2019·Bulletin of Experimental Biology and Medicine·N V NizyaevaA I Shchegolev
Dec 30, 2020·Clinical and Experimental Hypertension : CHE·Ya-Jing PanAi-Hua Zhang
Jan 27, 2021·The Journal of Obstetrics and Gynaecology Research·Ömer DemirMehmet A Osmanağaoğlu
Sep 4, 2020·American Journal of Obstetrics and Gynecology·Michal Fishel BartalBaha M Sibai

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