Proteomic analysis of the adaptation to warming in the Antarctic bacteria Shewanella frigidimarina

Biochimica Et Biophysica Acta
Laura García-DescalzoCristina Cid


Antarctica is subjected to extremely variable conditions, but the importance of the temperature increase in cold adapted bacteria is still unknown. To study the molecular adaptation to warming of Antarctic bacteria, cultures of Shewanella frigidimarina were incubated at temperatures ranging from 0°C to 30°C, emulating the most extreme conditions that this strain could tolerate. A proteomic approach was developed to identify the soluble proteins obtained from cells growing at 4°C, 20°C and 28°C. The most drastic effect when bacteria were grown at 28°C was the accumulation of heat shock proteins as well as other proteins related to stress, redox homeostasis or protein synthesis and degradation, and the decrease of enzymes and components of the cell envelope. Furthermore, two main responses in the adaptation to warm temperature were detected: the presence of diverse isoforms in some differentially expressed proteins, and the composition of chaperone interaction networks at the limits of growth temperature. The abundance changes of proteins suggest that warming induces a stress situation in S. frigidimarina forcing cells to reorganize their molecular networks as an adaptive response to these environmental conditions.


Aug 16, 2016·Chemistry & Biodiversity·Margarita R Marín-YaseliMarta Ruiz-Bermejo
Aug 15, 2017·Frontiers in Microbiology·Eva Garcia-Lopez, Cristina Cid


Jan 11, 1991·Nucleic Acids Research·I V BoniN V Tzareva
Aug 29, 1995·Proceedings of the National Academy of Sciences of the United States of America·L ChenJ D Helmann
Aug 11, 2000·Biological Chemistry·M SprinzlK Szkaradkiewicz
May 3, 2002·The Journal of Biological Chemistry·Tong-Shin ChangSue Goo Rhee
Aug 16, 2002·Current Opinion in Biotechnology·Ricardo CavicchioliKevin R Sowers
Feb 4, 2003·Nature Reviews. Molecular Cell Biology·José D Faraldo-Gómez, Mark S P Sansom
Feb 21, 2004·FEMS Microbiology Reviews·D GeorletteC Gerday
Jul 28, 2005·Molecular Microbiology·Andrew J Darwin
Sep 23, 2006·Proteomics·Ingrid MillerElisabetta Gianazza
Jun 2, 2007·Extremophiles : Life Under Extreme Conditions·Immacolata RuggieroMariorosario Masullo
Jun 15, 2007·Journal of Molecular Biology·Wakana Iwasaki, Kunio Miki
Aug 2, 2007·Canadian Journal of Microbiology·Bassam El-Fahmawi, George W Owttrim
May 22, 2009·FEMS Microbiology Letters·Sahayog Narayan Jamdar
Dec 23, 2009·Journal of Proteomics·Marise Fonseca dos SantosGilberto Barbosa Domont
Mar 24, 2010·Proceedings of the National Academy of Sciences of the United States of America·So NakagawaTakashi Gojobori
May 21, 2010·Environmental Microbiology·Lily TingRicardo Cavicchioli
Jul 16, 2010·DNA and Cell Biology·Patrick D SchlossJo Handelsman
Aug 24, 2010·Current Microbiology·M K ChattopadhyayS Shivaji
Apr 2, 2011·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Karla D Krewulak, Hans J Vogel
Jul 23, 2011·Molecular Cell·Giselle Román-HernándezTania A Baker
Mar 16, 2012·Journal of Proteomics·Medicharla Venkata Jagannadham, Chiranjit Chowdhury
Dec 4, 2012·Nucleic Acids Research·Andrea FranceschiniLars J Jensen

Related Concepts

Heat shock proteins
Enzymes, antithrombotic
Protein Biosynthesis
Shewanella frigidimarina
Enzymes for Treatment of Wounds and Ulcers
Molecular Chaperones

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Sexual Dimorphism in Neurodegeneration

There exist sex differences in neurodevelopmental and neurodegenerative disorders. For instance, multiple sclerosis is more common in women, whereas Parkinson’s disease is more common in men. Here is the latest research on sexual dimorphism in neurodegeneration

HLA Genetic Variation

HLA genetic variation has been found to confer risk for a wide variety of diseases. Identifying these associations and understanding their molecular mechanisms is ongoing and holds promise for the development of therapeutics. Find the latest research on HLA genetic variation here.

Super-resolution Microscopy

Super-resolution microscopy is the term commonly given to fluorescence microscopy techniques with resolutions that are not limited by the diffraction of light. Here are the latest discoveries pertaining to super-resolution microscopy.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.

Brain Lower Grade Glioma

Low grade gliomas in the brain form from oligodendrocytes and astrocytes and are the slowest-growing glioma in adults. Discover the latest research on these brain tumors here.

CD4/CD8 Signaling

Cluster of differentiation 4 and 8 (CD8 and CD8) are glycoproteins founds on the surface of immune cells. Here is the latest research on their role in cell signaling pathways.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.