Proteomics-Based Insights Into the SARS-CoV-2-Mediated COVID-19 Pandemic: A Review of the First Year of Research.

Molecular & Cellular Proteomics : MCP
Jeremy L Praissman, Lance Wells


In late 2019, a virus subsequently named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in China and led to a worldwide pandemic of the disease termed coronavirus disease 2019. The global health threat posed by this pandemic led to an extremely rapid and robust mobilization of the scientific and medical communities as evidenced by the publication of more than 10,000 peer-reviewed articles and thousands of preprints in the first year of the pandemic alone. With the publication of the initial genome sequence of SARS-CoV-2, the proteomics community immediately joined this effort publishing, to date, more than 100 peer-reviewed proteomics studies and submitting many more preprints to preprint servers. In this review, we focus on peer-reviewed articles published on the proteome, glycoproteome, and glycome of SARS-CoV-2. At a basic level, proteomic studies provide valuable information on quantitative aspects of viral infection course; information on the identities, sites, and microheterogeneity of post-translational modifications; and, information on protein-protein interactions. At a biological systems level, these studies elucidate host cell and tissue responses, characterize antibodies and other immune system...Continue Reading


Dec 9, 2003·Trends in Microbiology·Edward C Holmes
Feb 3, 2004·The Journal of Biological Chemistry·Paul TowlerMichael W Pantoliano
Apr 16, 2004·Molecular & Cellular Proteomics : MCP·Troels Zakarias KristiansenAkhilesh Pandey
Feb 25, 2006·Cell·Mark Marsh, Ari Helenius
Jan 29, 2008·Journal of Proteome Research·Robert SprungYingming Zhao
Dec 5, 2008·Microbiology and Molecular Biology Reviews : MMBR·Matthew Frieman, Ralph Baric
Nov 11, 2009·Proceedings of the National Academy of Sciences of the United States of America·Kailang WuFang Li
Mar 4, 2010·Annual Review of Biochemistry·Jason MercerAri Helenius
May 30, 2014·Nature·Min-Sik KimAkhilesh Pandey
Dec 18, 2014·Nucleic Acids Research·Peter V HornbeckElzbieta Skrzypek
Jan 24, 2015·Science·Mathias UhlénFredrik Pontén
Apr 16, 2015·Journal of Proteome Research·Nathan J EdwardsKaren A Ketchum
Dec 8, 2016·Nucleic Acids Research·Eric W DeutschJuan Antonio Vizcaíno
Apr 7, 2017·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Yuelong Shu, John McCauley
Nov 16, 2017·Nucleic Acids Research·UNKNOWN NCBI Resource Coordinators
Mar 1, 2018·Molecular & Cellular Proteomics : MCP·Vagisha SharmaBrendan MacLean
May 28, 2019·Virology Journal·Dewald Schoeman, Burtram C Fielding
Jun 22, 2019·Annual Review of Microbiology·To Sing Fung, Ding Xiang Liu
Oct 17, 2019·Glycobiology·William S YorkWenjin Zhang
Jan 25, 2020·The New England Journal of Medicine·Na ZhuUNKNOWN China Novel Coronavirus Investigating and Research Team
Feb 23, 2020·Science·Daniel WrappJason S McLellan
Mar 11, 2020·Cell·Alexandra C WallsDavid Veesler
Mar 14, 2020·Proceedings of the National Academy of Sciences of the United States of America·Shutoku MatsuyamaMakoto Takeda
Jun 1, 2018·Future Virology·To Sing Fung, Ding Xiang Liu
Apr 25, 2020·Cell·Dongwan KimHyeshik Chang
Apr 28, 2020·European Journal of Internal Medicine·Paolo VerdecchiaFabio Angeli
Apr 29, 2020·The European Respiratory Journal·Nicholas E IngrahamMichael A Puskarich
Apr 29, 2020·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Hisashi Kai, Mamiko Kai
May 6, 2020·Science·Yasunori WatanabeMax Crispin

❮ Previous
Next ❯

Software Mentioned


Related Concepts

Related Feeds

ASBMB Publications

The American Society for Biochemistry and Molecular Biology (ASBMB) includes the Journal of Biological Chemistry, Molecular & Cellular Proteomics, and the Journal of Lipid Research. Discover the latest research from ASBMB here.