PMID: 8600486Nov 1, 1995Paper

Prothrombotic effects of environmental stress: changes in platelet function, hematocrit, and total plasma protein

Psychosomatic Medicine
S M PattersonDavid S Goldstein

Abstract

Mental stress can affect a range of variables relevant to hemostasis and thrombosis. However, research has not clarified whether these effects occur as part of a generalized sympathoadrenal response or whether stress-induced increases in catecholamines and blood pressure have selective and independent effects on hematologic variables. This study assessed the effects of mental and cold pressor stress on platelet activation, hematocrit, and total plasma protein and the relationship of these changes to sympathoadrenal and hemodynamic mechanisms. Platelet factor 4, beta-thromboglobulin, total plasma protein, hematocrit values, and hemoglobin were measured in 22 healthy men (32 +/- 7 years) during rest, mental arithmetic, and cold pressor task. A no-stress control group of five male subjects was used to rule out the possible effects of blood withdrawal in producing these changes. Significant increases to mental arithmetic and cold pressor (p < .001) were observed in platelet factor 4 and beta-thromboglobulin. Increases (p < .002) in hematocrit values and total plasma protein also occurred with mental arithmetic and cold pressor. Correlational analyses revealed that changes in hematocrit and total plasma protein concentrations were r...Continue Reading

References

Jun 7, 1975·Lancet·P S BurgeT A Prankerd
Jul 12, 1979·The New England Journal of Medicine·T D NoakesR Dowdeswell
Jun 1, 1976·The American Journal of Cardiology·S G ChrysantG Neller
Nov 1, 1991·Psychosomatic Medicine·J H Markovitz, K A Matthews
Jan 1, 1991·Psychological Bulletin·T Kamarck, J R Jennings
Jan 1, 1991·Journal of Psychosomatic Research·S JernH Wadenvik
Nov 1, 1989·Thrombosis Research·A KusuiH Fukuzaki
Jan 1, 1989·British Journal of Haematology·C JernS Jern
Jan 1, 1985·Biorheology·L J WurzingerH Schmid-Schönbein
Jun 1, 1985·Circulation·S P LevineJ N George
Jan 1, 1987·Annals of the New York Academy of Sciences·V T TurittoV Fuster
Apr 21, 1988·The New England Journal of Medicine·A RozanskiD S Berman
Aug 1, 1986·Clinical Science·G D Lowe
Oct 16, 1986·The New England Journal of Medicine·D J FitzgeraldG A FitzGerald
Jun 11, 1987·The New England Journal of Medicine·J Hirsh
Aug 1, 1974·Journal of Applied Physiology·D B Dill, D L Costill
Oct 1, 1983·The American Journal of Cardiology·D FitchettM Ehrman
Jan 1, 1983·Acta Haematologica·L AndrénL Hansson
Nov 1, 1993·Psychosomatic Medicine·S M PattersonD S Krantz
Mar 1, 1958·The Journal of Clinical Investigation·F A FINNERTYR L GUILLAUDEU

❮ Previous
Next ❯

Citations

Jun 13, 1998·Psychosomatic Medicine·W J KopA Appels
Feb 24, 1999·Journal of Biomedical Materials Research·R BarbucciA M Aloisi
Jun 11, 2004·Psychophysiology·Jet J C S Veldhuijzen van ZantenDouglas Carroll
May 13, 2011·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Anthony W AustinRoland von Känel
Jul 17, 2019·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Allen A ChampagneDouglas J Cook
Jun 24, 1999·Journal of Biomedical Materials Research·R BarbucciA M Aloisi
Jun 14, 2000·Psychosomatic Medicine·A Camacho, J E Dimsdale
Jul 9, 2008·Journal of Behavioral Medicine·Stephen M PattersonCornelia A Patterson
Oct 28, 2005·International Journal of Behavioral Medicine·S M PattersonM F Muldoon
Jan 12, 2017·Biological Reviews of the Cambridge Philosophical Society·Christopher P JohnstoneRichard D Reina
Dec 9, 2009·Harvard Review of Psychiatry·Laura K Kent, Peter A Shapiro
Feb 22, 2005·Psychophysiology·Jet J C S Veldhuijzen van ZantenChristopher Ring
Jan 11, 2018·Oxidative Medicine and Cellular Longevity·Leonardo SandriniSilvia S Barbieri
Nov 1, 2013·World Journal of Psychiatry·Pia Koudouovoh-Tripp, Barbara Sperner-Unterweger
Jul 24, 2004·Psychosomatic Medicine·Philip C StrikeAndrew Steptoe
Oct 14, 2020·Proceedings of the National Academy of Sciences of the United States of America·Matthew T MeffordDavid R Williams

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.