PMID: 8949785Jan 1, 1996Paper

Proton and neutron radiation in cancer treatment: clinical and economic outcomes

Bulletin du cancer. Radiothérapie : journal de la Société française du cancer : organe de la société française de radiothérapie oncologique
F Fleurette, S Charvet-Protat

Abstract

The French National Agency for Medical Evaluation (ANDEM) was requested to assess the effectiveness of proton and neutron beam therapy in cancer treatment compared to conventional radiotherapy. This task was accomplished by a critical appraisal of the clinical and economic literature. According to the published economic literature and the capital and staffing cost analysis, it appears that the costs of proton therapy are likely to be two or three times greater than those of photon conformal therapy. According to the published clinical literature, proton beam therapy should be proposed as a routine treatment only for uveal melanoma and skull base cancers. Neutron beam therapy should be proposed as a routine treatment for inoperable salivary gland tumors; its use may be also discussed in cases of stage C-D1 prostate cancers and soft tissue sarcomas. Based on the current scientific evidence and given the incidence rate of these tumors, the time and material requirements, the current French proton/neutron beam facilities are able to meet the current demand. For other cancers the medical and economic potential of proton therapy is still an open question.

References

Sep 1, 1990·International Journal of Radiation Oncology, Biology, Physics·D LinstadtT L Phillips
Sep 1, 1989·International Journal of Radiation Oncology, Biology, Physics·J E MunzenriderP McManus
Nov 15, 1989·Cancer·G SchmittN Zamboglou
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Citations

Jun 30, 2009·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Deepak KhuntiaMinesh P Mehta
Oct 12, 2007·Medical Physics·J B FarrJ D Forman
Aug 19, 2008·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Madelon Pijls-JohannesmaYolande Lievens
May 16, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Mark LodgeTom Jefferson
Apr 12, 2003·Technology in Cancer Research & Treatment·Volker W StieberMinesh P Mehta
Jun 29, 2006·Head & Neck·Barbara Alicja Jereczek-FossaRoberto Orecchia

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