Proton beam irradiation using a light-field technique for the treatment of choroidal hemangiomas

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
R V Paul ChanIvana K Kim

Abstract

To describe the clinical outcomes of patients with circumscribed and diffuse choroidal hemangiomas treated by proton beam irradiation using a nonsurgical light-field technique. A retrospective chart review was performed on a series of 19 patients (19 eyes) with choroidal hemangiomas treated with proton beam therapy between July 1988 and August 2005. Choroidal hemangiomas were treated with proton beam irradiation using a light-field technique and doses ranging from 15 to 30 cobalt Gray equivalents (CGE; CGE = proton Gy x relative biological effectiveness 1.1) in 4 fractions. Patients with at least 6 months' follow-up were included in the study. Tumor regression, visual acuity, absorption of subretinal fluid, and treatment-associated complications were evaluated by clinical examination and ultrasonography. Visual acuity improved or remained stable in 14 of 18 eyes (78%). Subretinal fluid was initially present in 16 of 19 eyes (84%), and completely resolved in all 16 eyes. Tumor height, as measured by B-scan ultrasonography, decreased in 18 of 19 eyes and remained stable in 1 of 19, as of the last examination. Complications of radiation developed in 9 of 19 eyes (47%) with the total applied dose ranging from 15 to 30 CGE for these...Continue Reading

Citations

Dec 1, 2012·Eye·H HeimannB Damato
Jul 1, 2012·Asia-Pacific Journal of Ophthalmology·Syril Dorairaj, Robert Ritch
Apr 27, 2013·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Yoshihiro YonekawaShizuo Mukai
Jun 17, 2015·Survey of Ophthalmology·Eren Cerman, Osman Çekiç
Jun 25, 2015·Asia-Pacific Journal of Ophthalmology·Jessica S MaslinRobert Ritch
Oct 19, 2016·Acta Ophthalmologica·Yvonne KoenraadsUNKNOWN SWS study group
Mar 5, 2021·JAMA Ophthalmology·Carolina A Chiou, Evangelos Gragoudas
Apr 13, 2021·Ophthalmic Genetics·Martina FormisanoSolmaz Abdolrahimzadeh

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