PMID: 9543428Apr 16, 1998Paper

Proton T2 relaxation of cerebral metabolites during transient global ischemia in rat brain

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
H FujimoriJ Frahm

Abstract

Putative changes of metabolite T2 relaxation times were investigated before and after a 20-min period of global ischemia in rat brain in vivo (n = 10) using localized proton MRS at different echo times (2.35 T). Neither absolute T2 relaxation times (TE = 20-270 ms) nor time courses of T2-weighted metabolite signals (TE = 135 ms) revealed statistically significant changes during the occlusion or early reperfusion relative to pre-ischemic baseline. These findings are in line with reports of relaxation changes at much later stages and further demonstrate that altered T2 relaxation is not a confounding factor in diffusion-weighted long-TE proton MRS during early ischemic events.

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Citations

Jan 26, 2002·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Y KeP F Renshaw
Feb 3, 2016·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jens T RosenbergSamuel C Grant
May 14, 2004·Journal of the Neurological Sciences·Paul M WalkerFrançois Brunotte
Sep 11, 2014·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Noam ShemeshLucio Frydman
May 28, 2003·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Hao LeiWei Chen
Apr 26, 2007·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Shang-Yueh TsaiFa-Hsuan Lin

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