Proton transfer in histidine-tryptophan heterodimers embedded in helium droplets

The Journal of Chemical Physics
Bruno BellinaVitaly V Kresin

Abstract

We used cold helium droplets as nano-scale reactors to form and ionize, by electron bombardment and charge transfer, aromatic amino acid heterodimers of histidine with tryptophan, methyl-tryptophan, and indole. The molecular interaction occurring through an N-H···N hydrogen bond leads to a proton transfer from the indole group of tryptophan to the imidazole group of histidine in a radical cationic environment.

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Citations

Mar 31, 2018·Physical Review Letters·James D PickeringHenrik Stapelfeldt
Oct 22, 2018·The Journal of Chemical Physics·James D PickeringHenrik Stapelfeldt
Dec 9, 2020·Physical Chemistry Chemical Physics : PCCP·Lukas TiefenthalerOlof Echt
Nov 6, 2020·Chemical Reviews·Eric GloaguenMarkus Gerhards

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