PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels

Yongwook Choi, Agnes P Chan


We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mouse variants at both the genomic and protein levels. The web server is freely available and open to all users with no login requirements at Supplementary data are available at Bioinformatics online.


May 5, 2001·Genome Research·P C Ng, S Henikoff
Jul 11, 2006·Annual Review of Genomics and Human Genetics·Pauline C Ng, Steven Henikoff
Apr 1, 2010·Nature Methods·Ivan A AdzhubeiShamil R Sunyaev
Aug 19, 2011·Nature Reviews. Genetics·Gregory M Cooper, Jay Shendure
Oct 12, 2012·PloS One·Yongwook ChoiAgnes P Chan

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