Providing Appropriate Risk Information on Genome Editing for Patients

Trends in Biotechnology
Motoko Araki, Tetsuya Ishii

Abstract

Genome editing, represented by CRISPR/Cas9, facilitates somatic and germline gene modifications in many species, including humans. However, one of key issues, off-target mutation deserves special consideration prior to clinical applications. We herein discuss the importance of risk information on genome editing for obtaining legitimate patient consent and social acceptance.

References

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Jun 17, 2015·Trends in Molecular Medicine·Tetsuya Ishii

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Citations

Feb 11, 2016·The New England Journal of Medicine·R Alta Charo
Oct 25, 2016·Biochimica Et Biophysica Acta·Lang Yi, Jinming Li
Apr 11, 2017·Acta Pharmacologica Sinica·Gayong ShimYu-Kyoung Oh
Jul 18, 2018·Annals of Human Genetics·Sleiman Razzouk
Dec 2, 2017·European Journal of Human Genetics : EJHG·Heidi C HowardUNKNOWN Public and Professional Policy Committee of the European Society of Human Genetics
May 24, 2019·Protein Engineering, Design & Selection : PEDS·Sonali BhaktaToshifumi Tsukahara
Nov 21, 2019·The CRISPR Journal·Tetsuya Ishii, Iñigo de Miguel Beriain
Jul 18, 2017·Trends in Biotechnology·Amr A Abdeen, Krishanu Saha

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