Proximal Femur Hounsfield Units on CT Colonoscopy Correlate With Dual-energy X-ray Absorptiometry

Clinical Orthopaedics and Related Research
Daniel L ChristensenScott M Tintle

Abstract

Quantifying bone mineral density (BMD) on CT using commercial software demonstrates good-to-excellent correlations with dual-energy x-ray absorptiometry (DEXA) results. However, previous techniques to measure Hounsfield units (HUs) within the proximal femur demonstrate less successful correlation with DEXA results. An effective method of measuring HUs of the proximal femur from CT colonoscopy might allow for opportunistic osteoporosis screening. (1) Do proximal femur HU measurements from CT colonoscopy correlate with proximal femur DEXA results? (2) How effective is our single HU measurement technique in estimating the likelihood of overall low BMD? (3) Does the relationship between our comprehensive HU measurement and DEXA results change based on age, sex, or time between studies? This retrospective study investigated the measurement of HU of the femur obtained on CT colonoscopy studies compared with DEXA results. Between 2010 and 2017, five centers performed 9085 CT colonoscopy studies; of those, 277 (3%) also had available DEXA results and were included in this study, whereas 8809 (97%) were excluded for inadequate CT imaging, lack of DEXA screening, or lack of proximal femur DEXA results. The median number of days between C...Continue Reading

References

Oct 1, 1978·Seminars in Nuclear Medicine·C E Metz
Jun 1, 1991·Computer Methods and Programs in Biomedicine·J VermontJ Demongeot
Feb 2, 1995·The New England Journal of Medicine·S C Manolagas, R L Jilka
Aug 1, 1994·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·J A KanisN Khaltaev
Nov 9, 2000·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J A CauleyD Black
Oct 9, 2002·Journal of the American Geriatrics Society·Cynthia L LeibsonL Joseph Melton
May 26, 2004·Archives of Internal Medicine·Ethel S SirisMarc L Berger
Feb 3, 2005·Annals of Internal Medicine·Lisa M KernLinda P Fried
Nov 14, 2006·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Andrew J Vickers, Elena B Elkin
Dec 6, 2006·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Russel BurgeAnna Tosteson
Jan 9, 2008·Bone·John A KanisNikolai Khaltaev
Feb 5, 2009·JAMA : the Journal of the American Medical Association·Dana BliucJacqueline R Center
May 8, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·B AbrahamsenC Cooper
Dec 17, 2009·Archives of Internal Medicine·Amy Berrington de GonzálezCharles Land
Mar 13, 2010·European Journal of Radiology·Dirk K MuellerJoachim Erckenbrecht
Dec 29, 2010·Reviews in Endocrine & Metabolic Disorders·Erik Fink Eriksen
May 19, 2011·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Perry J PickhardtNeil Binkley
Jun 10, 2011·The Journal of Bone and Joint Surgery. American Volume·Joseph J SchreiberAnthony G Au
Jun 26, 2012·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Lang YangUNKNOWN Osteoporotic Fractures in Men (MrOS) Study Group
Jul 27, 2012·Tutorials in Quantitative Methods for Psychology·Kevin A Hallgren
Jan 22, 2014·The American Journal of Gastroenterology·Nicholas K WeberDavid H Bruining
Apr 29, 2014·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Nicole C WrightBess Dawson-Hughes
Jun 2, 2014·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Perry PickhardtNeil Binkley
Sep 4, 2014·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·F CosmanR Lindsay
Jan 17, 2015·European Radiology·Constantinus F BuckensPim A de Jong
Jan 17, 2015·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S Y LeeK H Sung
Jul 3, 2015·The Journal of Bone and Joint Surgery. American Volume·Joseph J SchreiberAndrew J Weiland
Oct 6, 2015·Journal of the American College of Radiology : JACR·Timothy J ZiemlewiczPerry J Pickhardt
Oct 21, 2016·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Timothy J ZiemlewiczPerry J Pickhardt
Jun 10, 2016·Journal of General Internal Medicine·Ethan A HalmBijal A Balasubramanian
Jun 16, 2016·JAMA : the Journal of the American Medical Association·UNKNOWN US Preventive Services Task ForceAlbert L Siu
Jun 23, 2016·Journal of Chiropractic Medicine·Terry K Koo, Mae Y Li
Apr 19, 2017·The Journal of Bone and Joint Surgery. American Volume·Scott C WagnerScott M Tintle
Sep 20, 2017·The Journal of Bone and Joint Surgery. American Volume·Elizabeth B GausdenJoseph M Lane
Oct 11, 2017·Radiologic Clinics of North America·Perry J Pickhardt

❮ Previous
Next ❯

Citations

Jul 1, 2020·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·D L ChristensenS M Tintle
May 23, 2021·Skeletal Radiology·Mohamad Farhan Mohamad AminNoorazrul Yahya
Dec 25, 2021·Military Medicine·Alan T VanierScott Wagner

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved