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Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1

Molecular Cell

Feb 4, 2005

Christopher R. VakocGerd A. Blobel

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Abstract

Recent evidence suggests that long-range enhancers and gene promoters are in close proximity, which might reflect the formation of chromatin loops. Here, we examined the mechanism for DNA looping at the beta-globin locus. By using chromosome conformation capture (3C), we show that the h...read more

Mentioned in this Paper

Enhancer brand
Gene Expression
DNA Sequence
Methionine
Phosphorylation
Operator gene
Cyclohexamide
Oligonucleotide Primers
Protein Biosynthesis
BCL2L1 gene
202
Paper Details
References
    • References31
    • Citations222
    • References31
    • Citations222
  • Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1

    Molecular Cell

    Feb 4, 2005

    Christopher R. VakocGerd A. Blobel

    PMID: 15694345

    DOI: 10.1016/j.molcel.2004.12.028

    Abstract

    Recent evidence suggests that long-range enhancers and gene promoters are in close proximity, which might reflect the formation of chromatin loops. Here, we examined the mechanism for DNA looping at the beta-globin locus. By using chromosome conformation capture (3C), we show that the h...read more

    Mentioned in this Paper

    Enhancer brand
    Gene Expression
    DNA Sequence
    Methionine
    Phosphorylation
    202
    Paper Details
    References
    • References31
    • Citations222
    • References31
    • Citations222
  • Get paper from

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