Proxy indicators to estimate appropriateness of antibiotic prescriptions by general practitioners: a proof-of-concept cross-sectional study based on reimbursement data, north-eastern France 2017

Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin
Nathalie ThillyCéline Pulcini

Abstract

BackgroundIn most countries, including France, data on clinical indications for outpatient antibiotic prescriptions are not available, making it impossible to assess appropriateness of antibiotic use at prescription level.AimOur objectives were to: (i) propose proxy indicators (PIs) to estimate appropriateness of antibiotic use at general practitioner (GP) level based on routine reimbursement data; and (ii) assess PIs' performance scores and their clinimetric properties using a large regional reimbursement database.MethodsA recent systematic literature review on quality indicators was the starting point for defining a set of PIs, taking French national guidelines into account. We performed a cross-sectional study analysing National Health Insurance data (available at prescriber and patient levels) on antibiotics prescribed by GPs in 2017 for individuals living in north-eastern France. We measured performance scores of the PIs and their case-mix stability, and tested their measurability, applicability, and room for improvement (clinimetric properties).ResultsThe 3,087 GPs included in this study prescribed a total of 2,077,249 antibiotic treatments. We defined 10 PIs with specific numerators, denominators and targets. Performance...Continue Reading

References

Dec 7, 2002·Quality & Safety in Health Care·S M CampbellM Marshall
Dec 7, 2007·Quality & Safety in Health Care·Samuel CoenenUNKNOWN ESAC Project Group
Jul 31, 2012·European Journal of Public Health·Céline PulciniPierre Verger
Sep 11, 2012·Antimicrobial Resistance and Infection Control·Dilip NathwaniWilliam Malcolm
Sep 18, 2012·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·C PulciniP Verger
Jan 31, 2013·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·C PulciniP Verger
Feb 13, 2016·JAMA : the Journal of the American Medical Association·Daniella MeekerJason N Doctor
Jul 20, 2016·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·C M A van den BoschS E Geerlings
Jan 23, 2017·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·B DemoréC Pulcini
Sep 20, 2017·PloS One·Carole TreibichBruno Ventelou
Nov 2, 2017·The Journal of Antimicrobial Chemotherapy·Philip HowardUNKNOWN ESGAP Indicators Working Group
Dec 29, 2017·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Daniel J LivorsiEli N Perencevich

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