Abstract
To describe the nature and the frequency of systemic diseases responsible for the pruritus sine materia. Value of this sign as a marker of malignancy. Prospective study undertaken over five years (1996-2001). generalized aspect of the pruritus and absence of specific primitive cutaneous lesions of an itching dermatosis. Parameters taken from the data of the anamnesis and the physical examination. Standard biologic and morphologic investigations were done. Ninety-five patients included (54 men, 41 women) of 55.5 years average age +/-18.1. In 24 patients, traditional hospitalisation with one average duration of eight days stay +/-3.15 was necessary. In 38 cases (40%), a systemic cause was found. The main conditions were: toxocariasis (8 cases), hematologic diseases (7 cases), chronic renal failure (6 cases), hypothyroidism (5 cases) and iron deficiency (5 cases). A neoplasm was found in eight cases (8,42%): seven hematologic malignancy (3 myeloma, 2 Hodgkin's diseases, 2 myeloproliferative syndromes) and one solid cancer (pulmonary adenocarcinoma). A systemic aetiology was observed in 38 cases (40%). The toxocariasis an underestimated disease comes at the first place. The pruritus sine materia can hide an hematologic malignancy.
References
Mar 12, 1977·British Medical Journal·J G ErskineG A Sekoni
Dec 1, 1976·Clinical and Experimental Dermatology·J M Beare
Sep 1, 1990·Cleveland Clinic Journal of Medicine·G R Kantor
Dec 1, 1989·Journal of the American Academy of Dermatology·F Rantuccio
Aug 1, 1988·Journal of the American Academy of Dermatology·C W Lober
Mar 1, 1986·Journal of the American Academy of Dermatology·S T Denman
Jun 1, 1987·Journal of the American Academy of Dermatology·R PaulC T Jansen
Sep 1, 1983·Journal of the American Academy of Dermatology·G R Kantor, D P Lookingbill
Apr 1, 1984·Journal of the American Academy of Dermatology·J A Savin
Sep 1, 1982·Clinical and Experimental Dermatology·R Camp
Feb 1, 1983·Archives of Dermatology·R D GoldmanJ Cinque
May 15, 1983·Cancer·P G GobbiE Ascari
Jan 1, 1982·Archives of Internal Medicine·B A Gilchrest
May 1, 1981·The American Journal of Medicine·M R FreedmanD R Ferguson
Jan 1, 1993·Journal of the American Academy of Dermatology·B F O'DonnellS O'Loughlin
Jan 13, 2000·International Journal of Dermatology·G Yosipovitch, M David
Nov 30, 2000·Dermatology : International Journal for Clinical and Investigative Dermatology·P HumbertT Barale
Aug 13, 2002·Dermatologic Clinics·Lawrence Etter, Sarah A Myers
Nov 16, 2002·BMJ : British Medical Journal·D Hugh RushtonIan D Ramsay
Feb 13, 1954·British Medical Journal·L FORMAN
Apr 1, 1989·Parasitology Today·P Prociv
Citations
Aug 13, 2014·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·T MettangU Raap
Dec 1, 2014·Annales de dermatologie et de vénéréologie·M Amy de la BretèqueE Mahé
Apr 4, 2006·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·T MettangE Weisshaar
Sep 17, 2008·Journal of the American Academy of Dermatology·Béatrice GavignetPhilippe Humbert
Nov 21, 2015·Der Internist·T MettangA E Kremer
Nov 22, 2005·Dermatologic Therapy·Margherita TerranovaTorello Lotti
Oct 4, 2007·International Journal of Dermatology·Anthony T-J GoonChee-Leok Goh
Jan 3, 2013·Veterinary Dermatology·Emmanuel BensignorPaola Cavana
Feb 27, 2014·Biochimica Et Biophysica Acta·Andreas E KremerRonald P J Oude Elferink
Jul 5, 2016·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·A E Kremer, T Mettang
May 14, 2020·Parasite : Journal De La Société Française De Parasitologie·Jean-François MagnavalAntoine Berry
Jun 28, 2019·Der Internist·A E Kremer, T Mettang
Dec 23, 2019·Clinics in Dermatology·Kalina Welz-KubiakJacek C Szepietowski