PSA and beyond: alternative prostate cancer biomarkers

Cellular Oncology (Dordrecht)
Sharanjot Saini

Abstract

The use of biomarkers for prostate cancer screening, diagnosis and prognosis has the potential to improve the clinical management of the patients. Owing to inherent limitations of the biomarker prostate-specific antigen (PSA), intensive efforts are currently directed towards a search for alternative prostate cancer biomarkers, particularly those that can predict disease aggressiveness and drive better treatment decisions. A literature search of Medline articles focused on recent and emerging advances in prostate cancer biomarkers was performed. The most promising biomarkers that have the potential to meet the unmet clinical needs in prostate cancer patient management and/or that are clinically implemented were selected. With the advent of advanced genomic and proteomic technologies, we have in recent years seen an enormous spurt in prostate cancer biomarker research with several promising alternative biomarkers being discovered that show an improved sensitivity and specificity over PSA. The new generation of biomarkers can be tested via serum, urine, or tissue-based assays that have either received regulatory approval by the US Food and Drug Administration or are available as Clinical Laboratory Improvement Amendments-based lab...Continue Reading

References

Feb 1, 1967·The Journal of Urology·G T MellingerJ Bailar
Apr 3, 2002·JAMA : the Journal of the American Medical Association·Mark A RubinArul M Chinnaiyan
May 28, 2004·The New England Journal of Medicine·Ian M ThompsonCharles A Coltman
Jul 13, 2004·The New England Journal of Medicine·Anthony V D'AmicoWilliam J Catalona
Jul 31, 2004·Trends in Biotechnology·Sergey E IlyinCarlos R Plata-Salamán
Jun 9, 2005·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Mark A RubinJan-Erik Johansson
Nov 10, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Robert D LobergKenneth J Pienta
Nov 16, 2006·JAMA : the Journal of the American Medical Association·Louise C WalterBadrinath R Konety
Aug 11, 2007·World Journal of Urology·Eric Schiffer
Oct 9, 2007·European Urology·Karim BensalahShahrokh F Shariat
Nov 21, 2007·Cancer Causes & Control : CCC·Ruth EtzioniEric Feuer
Dec 7, 2007·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Daniel C DanilaHoward I Scher
Feb 26, 2008·The Journal of Urology·Ina L DerasJack Groskopf
Mar 14, 2008·Nature Reviews. Cancer·Hans LiljaAndrew J Vickers
Apr 4, 2008·Nature·Charles L Sawyers
May 27, 2008·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Maisa YoshimotoJeremy A Squire
Jul 30, 2008·Proceedings of the National Academy of Sciences of the United States of America·Patrick S MitchellMuneesh Tewari
Oct 3, 2008·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Johann S de BonoDerek Raghavan
May 22, 2009·AJR. American Journal of Roentgenology·Gary J KelloffUNKNOWN Prostate Cancer Imaging Working Group
Jul 10, 2009·Urology·Virginie Vlaeminck-GuillemPhilippe Paparel
Sep 24, 2009·Cancer Research·Douglas R HurstDanny R Welch
Dec 17, 2009·The Journal of Urology·Jonathan I Epstein
Jan 20, 2010·Prostate Cancer and Prostatic Diseases·K RobinsonG D Dakubo
Mar 5, 2010·CA: a Cancer Journal for Clinicians·Andrew M D WolfUNKNOWN American Cancer Society Prostate Cancer Advisory Committee
Mar 12, 2010·Pharmaceutical Research·Sharanjot SainiRajvir Dahiya
Apr 1, 2010·Molecular Cancer Research : MCR·Jaroslaw SzczyrbaFriedrich Grässer
May 8, 2010·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Lori J SokollDaniel W Chan
Jun 11, 2010·Journal of the National Medical Association·Durado D BrooksIdris Guessous
Jul 6, 2010·Journal of Proteomics·Suresh MathivananRichard J Simpson
Sep 17, 2010·Genes & Development·Michael M Shen, Cory Abate-Shen
Sep 18, 2010·Clinical Chemistry·Jessica A WeberKai Wang
Dec 17, 2010·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Sharanjot SainiRajvir Dahiya
Jan 5, 2011·European Urology·Diederick DuijveszGuido Jenster
Jan 29, 2011·Journal of Magnetic Resonance Imaging : JMRI·Yousef MazaheriHedvig Hricak

❮ Previous
Next ❯

Citations

Jun 22, 2017·Expert Review of Molecular Diagnostics·Minke SmitsJack A Schalken
Feb 10, 2018·Current Treatment Options in Oncology·Cristóbal Sanhueza, Manish Kohli
Jun 26, 2018·Expert Review of Molecular Diagnostics·Emily C LydonEphraim L Tsalik
Oct 27, 2018·Cellular Oncology (Dordrecht)·Mª Luisa PeceroSonia Molina-Pinelo
Apr 6, 2019·Current Drug Targets·Maryam Zanjirband, Soheila Rahgozar
Oct 30, 2019·Cancer Metastasis Reviews·Afshin MoradiJyotsna Batra
Dec 31, 2019·Journal of Cellular Biochemistry·Ning HanLili Yu
Jan 4, 2019·Clinical Chemistry·Klaus PantelHoward I Scher
Apr 8, 2017·Oncotarget·Henry A AdeolaLuiz F Zerbini
Jun 9, 2020·Clinical and Translational Medicine·Longxiang WuZhenyu Ou
Sep 4, 2020·World Journal of Clinical Oncology·Dwayne TuckerXuesen Dong
Apr 9, 2020·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Á Rodríguez PérezD Benítez-Ribas
Jun 3, 2020·Genetics and Molecular Biology·Monyse de NóbregaIlce Mara de Syllos Cólus
Mar 1, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Yujie SunGuojun Zhang
Dec 20, 2018·International Journal of Molecular Sciences·Evgeniy A LekchnovPavel P Laktionov
Aug 18, 2017·Wiley Interdisciplinary Reviews. RNA·Ovidiu BalacescuCatalin Marian
Aug 23, 2018·Prostate Cancer and Prostatic Diseases·E David CrawfordLaurence Klotz
Nov 13, 2019·Scientific Reports·Irengbam Rocky MangangchaR K Brojen Singh
Mar 29, 2018·Molecular Cancer Research : MCR·Avital LevWafik S El-Deiry
Feb 14, 2018·Cancer Research·Divya BhagirathSharanjot Saini
Dec 9, 2020·Biosensors & Bioelectronics·Ana Díaz-FernándezPedro Estrela
Jan 9, 2021·Briefings in Bioinformatics·Qing-Wen WuChun-Hou Zheng
Aug 11, 2019·Clinica Chimica Acta; International Journal of Clinical Chemistry·Priscila Marcelino Dos Santos SilvaMaria Tereza Dos Santos Correia
Nov 1, 2020·Molecular & Cellular Proteomics : MCP·Rebeca KawaharaGiuseppe Palmisano
Nov 7, 2020·Biochimica Et Biophysica Acta. Reviews on Cancer·Divya ThomasPrakash Radhakrishnan
Jul 28, 2020·Urologic Oncology·Jennifer A StockertAshutosh K Tewari
Dec 25, 2019·Critical Reviews in Oncology/hematology·Jingpu WangYong Li

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Genomics (Keystone)

Cancer genomics approaches employ high-throughput technologies to identify the complete catalog of somatic alterations that characterize the genome, transcriptome and epigenome of cohorts of tumor samples. Discover the latest research using such technologies in this feed.

Related Papers

Science Translational Medicine
John R PrensnerArul M Chinnaiyan
Expert Review of Proteomics
Samantha E T LarkinPaul A Townsend
© 2022 Meta ULC. All rights reserved