PSA lo and behold: prostate cancer stem cells.

Cell Stem Cell
Max S Wicha

Abstract

Human prostate cancers contain multiple cell populations marked by varying levels of the differentiation marker prostate-specific antigen (PSA). In this issue of Cell Stem Cell, Qin et al. (2012) show that PSA(-/lo) cells are enriched for cells with tumor-initiating characteristics and may participate in resistance to androgen-ablative therapies.

Citations

Feb 2, 2018·Scientific Reports·Nupam P MahajanKiran Mahajan

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