Pseudo-Multicomponent Reactions of Arynes with N-Aryl Imines

The Journal of Organic Chemistry
Juan-Carlos CastilloYoann Coquerel

Abstract

Pseudo-three-component reactions are described for the conversion of simple N-aryl imines into 1,2-dihydroisoquinoline-type products. The approach relies on a regioselective cascade reaction involving two equivalents of the aryne component iteratively as a dienophile and as an electrophile. Some examples of related, more complex pseudo-four-component cascade processes are also reported.

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Sep 3, 2011·Angewandte Chemie·Hiroto YoshidaKen Takaki
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Jun 19, 2015·Organic Letters·Juan-Carlos CastilloYoann Coquerel

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Citations

Aug 4, 2016·Organic Letters·Sung-Eun Suh, David M Chenoweth
Jan 18, 2017·The Journal of Organic Chemistry·I N Chaithanya KiranYun He
Jan 20, 2017·Chemical Communications : Chem Comm·Jing-Kun XuShi-Kai Tian
Oct 19, 2016·Chemical Society Reviews·José-Antonio García-López, Michael F Greaney
Nov 3, 2016·Organic & Biomolecular Chemistry·C T Fathimath SalfeenaB S Sasidhar
Aug 10, 2018·Organic & Biomolecular Chemistry·Yesu AddepalliYun He
Feb 19, 2021·Chemical Reviews·Jiarong ShiYang Li

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