Abstract
To assess the potential risks associated with the environmental exposure of beta-lactam antibiotics (BLAs), the monitoring of the occurrence, distribution, and fate of these emerging contaminants in the environment is required. Herein, we demonstrate a molecularly imprinted solid-phase extraction (MISPE) method for selective and reliable screening of trace BLAs in river and tap water. By developing a low-temperature photopolymerization, highly selective molecularly imprinted polymers (MIPs) for five BLAs (penicillin G, amoxicillin, ampicillin, nafcillin and mezlocillin) were synthesized. Nafcillin was chosen as a pseudo template to make the MIP sorbent (Nafc-MIP), which was used in pseudo-template MISPE for preconcentration of the other four BLAs from river and tap water. The application of pseudo-template MISPE overcomes the template bleeding, which significantly elevates the sample background and restricts the application of MIP for detection of the target BLA below 2 microg/L. The average recoveries of BLAs are in the range of 60-90% when Nafc-MIP was adopted as the selective MISPE sorbent. The developed method was validated, and applied to the screening of trace beta-lactam antibiotics in river and tap water. The linearity ...Continue Reading
References
Apr 20, 2004·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Robert J UmplebyKen D Shimizu
Dec 29, 2004·Chemosphere·Haruhiko NakataJohn P Giesy
Apr 6, 2006·Journal of Chromatography. a·J M ChaK H Carlson
Feb 26, 2008·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Raphaël Denooz, Corinne Charlier
Feb 15, 2007·Talanta·Sérgio M SantosValdemar I Esteves
Citations
Apr 27, 2013·The Analyst·Deli XiaoNan Li
Feb 22, 2014·Environmental Science and Pollution Research International·Haidong ZhouYong Zhan
Oct 5, 2014·Environmental Science and Pollution Research International·Dan-Lian HuangChao Huang
Jan 29, 2011·Journal of Hazardous Materials·Xubiao LuoShenglian Luo
Jan 11, 2012·Environmental Pollution·Bo PanBaoshan Xing
Mar 19, 2015·Journal of Analytical Methods in Chemistry·Mónica Díaz-BaoPatricia Regal
Apr 12, 2014·Journal of Separation Science·Mohammad BehbahaniAkbar Bagheri
Dec 15, 2010·Rapid Communications in Mass Spectrometry : RCM·Hsin-Pin HoMaw-Rong Lee
Apr 5, 2014·Journal of Molecular Recognition : JMR·Michael J WhitcombeIan A Nicholls
Sep 22, 2012·Journal of Separation Science·Xiuxiu LiRongxian Zhang
May 18, 2020·Environmental Monitoring and Assessment·Cansu Ilke KuruSinan Akgöl
Dec 22, 2017·Environmental Science and Pollution Research International·Paula S PintoRochel M Lago
Jan 1, 2011·Analytical Methods : Advancing Methods and Applications·Junfa YinHailin Wang
Oct 21, 2019·Journal of Chromatography. a·Ali Azizi, Christina S Bottaro
Mar 25, 2021·The Science of the Total Environment·Chongjun ZhangDandan Zhou
Apr 27, 2021·Analytica Chimica Acta·Francesca TorriniMaria Minunni