PMID: 16623262Apr 21, 2006Paper

Pseudoallescheria boydii (Scedosporium apiospermum), cause of mycotic granulomatous osteomyelitis--case diagnosis

Srpski arhiv za celokupno lekarstvo
Jelena SoptaAleksandar Lesić

Abstract

Fungal bone infections constitute about 0.1-0.2% of all osteomyelitis cases. The disease, mycetoma pedis, most often affects the feet and is also known as madura foot. Mycetoma, extremely rare in this geographic area, is endemic in tropical and subtropical regions. We present a case of mycetoma pedis (madura foot). The patient was a 50-year-old woman. The clinical signs included pain, indurations, and local redness. The anamnesis was very long, about 10 years. The operative material was routinely stained with haematoxylin-eosine [HE]. Granulomatous inflammation of the bone was confirmed pathologically. All pathological characteristics pointed to a fungal infection in the form of mycetoma pedis. Special staining for fungi was performed: PAS, Grocott's hexamine-silver, and Giemsa, confirming the diagnosis of mycetoma. A definitive microbiological analysis was carried out through tissue inoculation on the Sabouraud dextrose agar laboratory media for fungal cultivation. Pseudoallescheria boydii, the sexual stage of Monosporium apiospermum, was isolated. After microbiological verification of fungal infection, surgical therapy was carried out. Seven months after the first operation, the patient had the same clinical signs. The diagno...Continue Reading

References

Jan 1, 1990·International Orthopaedics·J F SuttnerH Seeliger
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Oct 11, 2002·Archives of Dermatology·Adrienne M Feasel, Jaime A Tschen

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Citations

Jan 19, 2008·Clinical Microbiology Reviews·Karoll J CortezThomas J Walsh
Jun 14, 2017·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Jaya KochenburgerLaura Hoyt

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