PMID: 9659260Jul 11, 1998Paper

Pseudoangiomatous hyperplasia of mammary stroma associated with gynaecomastia

Journal of Clinical Pathology
M F MilaneziF C Schmitt

Abstract

To evaluate the prevalence of pseudoangiomatous hyperplasia of mammary stroma in gynaecomastia and its immunohistochemical profile in this setting. Eighty eight cases of gynaecomastia recovered from the files of the department of pathology, Botucatu School of Medicine from 1976 to 1996 were studied. In the cases associated with pseudoangiomatous hyperplasia of mammary stroma, immunoreactivity for cytokeratins (CAM 5.2), vimentin, CD34, factor VIII related antigen, and the oestrogen and progesterone receptors were studied. Pseudoangiomatous hyperplasia of mammary stroma was found in 21 of 88 cases of gynaecomastia (23.8%). In all cases, the cells lining the spaces were positive for vimentin, whereas CAM 5.2 and factor VIII related antigen were consistently negative. Nineteen of the 21 cases showed immunoreactivity for CD34. Ductal epithelial cells were positive for both the oestrogen receptor and the progesterone receptor, whereas stromal cells were negative. Pseudoangiomatous hyperplasia of mammary stroma was present in approximately one quarter of the cases of gynaecomastia. This immunohistochemical study confirms the mesenchymal origin of the stromal cells that line the pseudovascular spaces, as has been found in female cases...Continue Reading

References

Feb 1, 1986·Human Pathology·M F VuitchR A Erlandson
Feb 1, 1971·The Journal of Clinical Endocrinology and Metabolism·G L NicolisJ L Gabrilove
May 1, 1995·Histopathology·S Badve, J P Sloane
Mar 1, 1995·The American Journal of Surgical Pathology·C M PowellP P Rosen
Jan 1, 1963·Archivio di patologia e clinica medica·A LODI, P RAPINO

❮ Previous
Next ❯

Citations

Mar 28, 2008·Surgery Today·Yasuhiro SasakiJun-ichi Ogawa
Dec 18, 2007·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Marco FerreiraErika Resetkova
Apr 11, 2002·American Journal of Clinical Oncology·Claudia Y CastroAysegul A Sahin
May 11, 2002·Critical Care Medicine·Richard S HotchkissIrene E Karl
Nov 16, 2005·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Naruto TairaShigemitsu Takashima
Dec 6, 2006·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Kae OkoshiHisato Kobayashi
Sep 17, 2008·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Abid IrshadBeata Panzegrau
Dec 10, 2015·Radiology Case Reports·Eman AlmohawesMaria Arafah
Jun 9, 2009·Current Problems in Surgery·Kristin L CoxV Suzanne Klimberg
May 16, 2012·The Breast Journal·Erin BowmanHarvey L Bumpers
Feb 8, 2005·The Breast : Official Journal of the European Society of Mastology·J S LeeK W Min
Oct 5, 2010·International Journal of Surgery·S S JaunooP Dunn
Apr 27, 2004·Diagnostic Cytopathology·Philip C W LuiGary M K Tse
Jul 28, 2016·International Journal of Surgical Pathology·Canan Kelten TaluErol Rustu Bozkurt
Jul 30, 2003·The Prostate·Andrew B SmithermanJames L Mohler
Apr 4, 2008·The Breast Journal·Ari-Nareg MeguerditchianSwati Kulkarni
Feb 9, 2012·The American Journal of Surgical Pathology·Robert KornegoorPaul J van Diest
Jul 9, 2002·The Breast Journal·Liron Pantanowitz, James L Connolly
Oct 24, 2001·The Journal of Pathology·J A Walker, P Quirke
Jul 9, 2003·The Breast Journal·Murray H Seltzer, Marietta Kintiroglou
Aug 25, 2011·International Journal of Surgical Pathology·Eva K DrinkaPrabha Rajan
Feb 5, 2002·Archives of Pathology & Laboratory Medicine·Lina WangRichard J Cote
Jul 1, 2010·Archives of Pathology & Laboratory Medicine·Renu K Virk, Ashraf Khan
Aug 6, 2009·Archives of Pathology & Laboratory Medicine·Badr AbdullGaffar
Dec 1, 2001·Science·R S HotchkissI E Karl

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.