Pseudogenes contribute to the extreme diversity of nuclear ribosomal DNA in the hard coral Acropora

Molecular Biology and Evolution
Luis M MárquezM J H Van Oppen

Abstract

One characteristic of Indo-Pacific Acropora spp. is extremely high diversity in rDNA sequences at both the species and individual levels. In order to test the hypothesis that pseudogenes may contribute to this diversity, three kinds of analyses were conducted. First, for A. millepora (the species containing the most diverse suite of rDNA types), RT-PCR was used to determine which 5.8S rDNA types are expressed. Second, as previous studies have indicated that interspecific hybridization has occurred in the genus Acropora and silencing of rDNA loci via nucleolar dominance has been shown in some cases to involve methylation, patterns of variation were examined at methylation-susceptible sites. Third, patterns of substitution at conserved sites (including those that are likely to contribute to secondary structure in rRNA) in the 5.8S rDNA were examined. These analyses consistently indicated that one rDNA sequence type present in a broad range of Indo-Pacific Acropora species is likely to consist predominantly of pseudogenes. Patterns of variation also suggest that species may differ with respect to which rDNA sequence types have been silenced and which are active. These pseudogenes are likely to have arisen as a consequence of the i...Continue Reading

Citations

Oct 25, 2008·Journal of Molecular Evolution·Anne ChenuilJean-Pierre Féral
Apr 22, 2006·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Marta GromichoMaria João Collares-Pereira
Jun 9, 2005·Current Opinion in Microbiology·Thomas A Richards, David Bass
Jan 19, 2008·Theory in Biosciences = Theorie in Den Biowissenschaften·Athanasius F BompfünewererChristina Witwer
May 12, 2011·Integrative and Comparative Biology·Catherine S McFaddenScott C France
Feb 26, 2009·BMC Evolutionary Biology·Zac H ForsmanRobert J Toonen
Apr 2, 2011·BMC Research Notes·Ayalew B MentewabRebekah A Flowers
Sep 11, 2008·Journal of Molecular Evolution·Annette W Coleman, Madeleine J H van Oppen
Oct 14, 2005·Biological Reviews of the Cambridge Philosophical Society·Alexander M Kerr
Aug 19, 2004·Molecular Ecology·Steven V Vollmer, Stephen R Palumbi
Jun 2, 2009·Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology·Sabine Giessler, Claudia C Englbrecht
Oct 24, 2006·Molecular Ecology·Madeleine J H van Oppen, Ruth D Gates
Jan 27, 2007·Molecular Phylogenetics and Evolution·Catalina Aguilar, Juan Armando Sánchez
Sep 28, 2006·Journal of Biochemistry and Molecular Biology·Botlagunta MahendranSubhas C Kundu
May 23, 2015·Science·Colomban de VargasEric Karsenti
Jul 6, 2010·Molecular Phylogenetics and Evolution·D E MartínezR D Campbell
Mar 12, 2015·Memórias do Instituto Oswaldo Cruz·María Angeles ZuriagaMaría Dolores Bargues
Nov 28, 2016·Molecular Ecology Resources·Roberto ArrigoniValérie Barbe
Sep 27, 2007·Evolution; International Journal of Organic Evolution·Liam J RevellJonathan B Losos
May 15, 2020·Diseases of Aquatic Organisms·Henry S Lane, J Brian Jones
Apr 8, 2009·Molecular Phylogenetics and Evolution·Jianpeng XuJie Qi

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