Abstract
We investigated in detail the difference between serum and plasma potassium levels in patients with several conditions associated with pseudohyperkalemia. In total, 435 patients with either thrombocytoses, erythrocytoses, leucocytoses, or a mixed-type disorder and 30 healthy controls were included. In each case, the index Dk [serum potassium minus plasma potassium] and the index Dk100 (Dk x 100,000/platelets), which indicates the Dk value that corresponds to platelets of 100,000/mm(3), were estimated. Median Dk was significantly higher in the groups with platelet, erythrocyte, or mixed-type disorders than in the controls (P=0.001). Among these groups, Dk values were significantly higher in patients with thrombocytosis or mixed-type disorders compared with those with erythrocytosis (P<0.001, for both). Furthermore, no significant difference was observed in Dk values between controls and patients with white blood cell disorders (P=0.74). Dk values did not exceed 2.61 mmol/L, whereas Dk100 values were inversely related to platelet counts (r=-0.351, P<0.01). In conclusion, pseudohyperkalemia is mainly present in patients with thrombocytosis or mixed-type disorders, probably as a result of the degranulation of platelets, which offer...Continue Reading
References
Oct 10, 1991·The New England Journal of Medicine·M W NijstenA S Dofferhoff
Aug 20, 1988·BMJ : British Medical Journal·S H RalstonR D Sturrock
Apr 15, 1988·Revue médicale de Liège·P Franchimont
Sep 28, 1985·British Medical Journal·D J KerrJ H Dagg
Feb 28, 1986·Deutsche medizinische Wochenschrift·B Mödder, I Meuthen
Feb 17, 1966·The New England Journal of Medicine·W R BronsonE Cotlove
Feb 9, 1970·JAMA : the Journal of the American Medical Association·L C Chumbley
Jun 1, 1980·Postgraduate Medical Journal·D O Ho-Yen, C R Pennington
Feb 1, 1993·American Journal of Hematology·J J Michiels
May 1, 1958·The Journal of Clinical Investigation·R C HARTMANND P JACKSON
Citations
Mar 1, 2012·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Helen DickinsonDenise K Bonney
Aug 10, 2010·Computer Methods in Biomechanics and Biomedical Engineering·Mashhour Bani Amer
Nov 3, 2012·JAAPA : Official Journal of the American Academy of Physician Assistants·Johanna L ChelcunKenneth Friedman
Dec 1, 2009·Journal of Medical Case Reports·Abdallah GearaSuzanne El-Sayegh
Jul 2, 2008·Clinical Medicine & Research·Nikolaos SevastosAthanasios J Archimandritis
Nov 13, 2009·World Journal of Gastroenterology : WJG·Xiao-Yan CaiXiu-Jun Cai
Jun 1, 2013·North American Journal of Medical Sciences·Jaya R AsirvathamLoring Bjornson
Jun 17, 2014·The Journal of Emergency Medicine·Boris KhodorkovskyBarry Hahn
Sep 7, 2014·Clinical Biochemistry·Kayleigh R Davis, Martin A Crook
Mar 15, 2014·Biochemia Medica·Raffick A R Bowen, Alan T Remaley
May 24, 2011·International Journal of Nephrology·Stephen I Rifkin
Aug 31, 2010·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Masanori SeimiyaFumio Nomura
May 22, 2010·Hematology/oncology Clinics of North America·Bruce D AdamsSusan Spencer
Oct 14, 2009·Clinical Biochemistry·Raffick A R BowenAlan T Remaley
Aug 4, 2009·Emergency Medicine Clinics of North America·Bruce D AdamsSusan Spencer
Jul 22, 2008·Clinica Chimica Acta; International Journal of Clinical Chemistry·Hong-Kee LeeKiang-Teck J Yeo
Jul 18, 2009·American Journal of Hematology·Neha R ChawlaRonald L Sham
Apr 3, 2008·ANZ Journal of Surgery·James E F FitzgeraldCharles A Maxwell-Armstrong
Nov 20, 2008·International Journal of Laboratory Hematology·Y L OngM El-Agnaf
Oct 17, 2014·Critical Reviews in Clinical Laboratory Sciences·Qing H Meng, Elizabeth A Wagar
Oct 16, 2016·Scandinavian Journal of Clinical and Laboratory Investigation·Árpád LábadiGábor L Kovács
Jan 15, 2009·American Journal of Clinical Pathology·Bakul I Dalal, Malcolm L Brigden
Dec 6, 2011·JRSM Short Reports·Gurdeep Singh Mannu, Angeline Bhalerao
Mar 30, 2016·Lab on a Chip·Mokhamad Fakhrul UlumDedy Hermawan Bagus Wicaksono
Mar 3, 2015·Annals of Laboratory Medicine·Dae-Hyun KoWon-Ki Min
Jan 29, 2008·Clinical Chemistry·Boban AbrahamJoshua A Bornhorst
Apr 3, 2018·Laboratory Medicine·Jing Cao, Amy B Karger
Feb 24, 2020·International Urology and Nephrology·Hamid MazdakMehdi Gholampour
Oct 6, 2020·Annals of Clinical Biochemistry·Thomas G MorrisMehdi Mirzazadeh
Jan 26, 2021·Veterinary and Animal Science·Z RodriguezG Cramer
Mar 21, 2013·Annals of Clinical Biochemistry·M A Crook