Pseudohypo-aldosteronism and cholelithiasis: coincidence or pathogenetic correlation?

European Journal of Pediatrics
I AkkurtC Ringenberg

Abstract

Cholelithiasis is being documented with increasing frequency in the paediatric age group. Causes of gallstone formation in infants and neonates seem to differ from those in older children and adolescents. Two infants with pseudohypo-aldosteronism and cholelithiasis are reported. Salt-wasting and dehydration in pseudohypo-aldosteronism are suggested to be the pathogenetic mechanisms leading to gallstone formation possibly beginning in fetal life. The diagnosis of pseudohypo-aldosteronism may be missed, when salt-wasting is transitional. Cholelithiasis may go undetected when asymptomatic. CONCLUSION Pseudohypo-aldosteronism should be considered in infants with cholelithiasis even without obvious salt-wasting signs. Routine ultrasonographic screening for gallstones should be performed in patients with pseudohypo-aldosteronism.

Citations

Mar 10, 2001·Indian Journal of Pediatrics·E C CitakA Zengin
Nov 27, 2007·European Journal of Pediatrics·Pierre RobitailleJosée Dubois
Dec 24, 1997·Molecular and Cellular Endocrinology·U Kuhnle
Apr 12, 2000·Kidney International·O Bonny, E Hummler
Jan 29, 2011·Journal of Clinical Research in Pediatric Endocrinology·Selim KurtoğluDilek Çoban
Feb 24, 2016·Case Reports in Endocrinology·Najya A Attia, Yousef I Marzouk
Jun 15, 2011·Molecular and Cellular Endocrinology·Maria-Christina ZennaroFábio L Fernandes-Rosa
Jan 1, 2013·Endocrinology, Diabetes & Metabolism Case Reports·N AminT Mushtaq
Sep 30, 2016·Pediatrics International : Official Journal of the Japan Pediatric Society·Özmert Ma ÖzdemirHacer Ergin
Jan 29, 1999·Physiological Reviews·J M Pilewski, R A Frizzell
Mar 28, 2012·Hormones : International Journal of Endocrinology and Metabolism·Ioannis D KostakisDespina Perrea
Apr 16, 2014·Pediatrics International : Official Journal of the Japan Pediatric Society·Tetsuya KibeIkuya Ueta
May 1, 2007·Expert Review of Endocrinology & Metabolism·Felix G Riepe
Aug 23, 2002·Journal of the American Society of Nephrology : JASN·Olivier Bonny, Bernard C Rossier
Apr 25, 2019·Hormone Research in Pædiatrics·Atilla CayirHuseyin Demirbilek

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