PMID: 6402090Jan 29, 1983Paper

Pseudomonas aeruginosa colonisation in an intensive therapy unit: role of cross infection and host factors

British Medical Journal
M R NooneK B Rogers

Abstract

Despite the sparsity of Pseudomonas aeruginosa in the environment colonisation and infection with this organism was found at several sites by selective culture in 20 out of 46 patients in an intensive therapy unit. Three patients developed Ps aeruginosa pneumonia. Serial serogrouping and phage typing identified multiple strains in the unit and in the same patient. Rectal carriage occurred in 16 patients but rectal strains did not subsequently appear in tracheal aspirates; strains varied in their affinity for the upper respiratory tract. Colonisation was not directly related to length of stay and was detected in 16 of those colonised within 24 hours of admission. In intubated patients, who were colonised more frequently than those not intubated, upper respiratory tract colonisation correlated strongly with low initial arterial pH values. Personnel were probably responsible for cross infection among patients when the unit was busy. Strain differences and the susceptibility of patients also influenced colonisation and infection. Elimination of major reservoirs of Ps aeruginosa and compliance with procedures to control cross infection remain essential if patients in hospital are to escape colonisation by the organism.

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Citations

Apr 1, 1985·European Journal of Clinical Microbiology·T L PittS W Im
Jun 1, 1987·European Journal of Clinical Microbiology·N J LegakisJ Papavassiliou
Jan 1, 1989·Journal of Clinical Microbiology·S K MurthyP B Michelsen
Jun 1, 1993·Epidemiology and Infection·G DöringC Wolz
Oct 6, 1999·American Journal of Respiratory and Critical Care Medicine·M J BontenE E Stobberingh
Dec 1, 1993·The Journal of Hospital Infection·N A Ismaeel
Sep 1, 1991·Oral Surgery, Oral Medicine, and Oral Pathology·Y B WahlinM Sjöström
Feb 24, 2001·The Medical Clinics of North America·B A Cunha
Sep 1, 2004·FEMS Microbiology Letters·Joy HambrookChristopher Lindsay
Sep 14, 1995·British Journal of Nursing : BJN·R Horton
Oct 1, 1991·Journal of Advanced Nursing·D Gould
Sep 1, 1987·Pediatric Pulmonology·M J ThomassenC F Doershuk
Jan 7, 2000·British Journal of Nursing : BJN·L J Parker
Oct 24, 2002·Critical Care Medicine·Stefan ReuterMatthias Trautmann
Jan 30, 2020·Nature Communications·Kelly E R BachtaAlan R Hauser

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