Pseudomonas aeruginosa Colonization in the Intensive Care Unit: Prevalence, Risk Factors, and Clinical Outcomes

Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
Anthony D HarrisJudith A Johnson

Abstract

To determine the prevalence of Pseudomonas aeruginosa colonization on intensive care unit (ICU) admission, risk factors for P. aeruginosa colonization, and the incidence of subsequent clinical culture with P. aeruginosa among those colonized and not colonized. We conducted a cohort study of patients admitted to a medical or surgical intensive care unit of a tertiary care hospital. Patients had admission perirectal surveillance cultures performed. Risk factors analyzed included comorbidities at admission, age, sex, antibiotics received during current hospitalization before ICU admission, and type of ICU. Of 1,840 patients, 213 (11.6%) were colonized with P. aeruginosa on ICU admission. Significant risk factors in the multivariable analysis for colonization were age (odds ratio, 1.02 [95% CI, 1.01-1.03]), anemia (1.90 [1.05-3.42]), and neurologic disorder (1.80 [1.27-2.54]). Of the 213 patients colonized with P. aeruginosa on admission, 41 (19.2%) had a subsequent clinical culture positive for P. aeruginosa on ICU admission and 60 (28.2%) had a subsequent clinical culture positive for P. aeruginosa in the current hospitalization (ICU period and post-ICU period). Of these 60 patients, 49 (81.7%) had clinical infections. Of the 1,6...Continue Reading

References

Feb 1, 1992·Journal of Clinical Epidemiology·M Von KorffK Saunders
Aug 10, 2006·The Journal of Antimicrobial Chemotherapy·Alexandre Prehn ZavasckiLuciano Zubaran Goldani
May 16, 2007·Intensive Care Medicine·Antonella AgodiCarmelo Denaro
Jun 15, 2007·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Heather P GreenAnthony D Harris
Feb 19, 2008·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Ebbing LautenbachJoel Maslow
Jun 15, 2011·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Anthony D HarrisJon P Furuno
Aug 1, 2012·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Felipe F TuonJaime L Rocha
Feb 2, 2013·Intensive Care Medicine·Mario TumbarelloMassimo Antonelli
Jan 29, 2014·Infectious Disease Reports·David A EnochJohannis Andreas Karas
Mar 29, 2014·The New England Journal of Medicine·Shelley S MagillUNKNOWN Emerging Infections Program Healthcare-Associated Infections and Antimicrobial Use Prevalence Survey Team
Oct 2, 2014·The Journal of Clinical Investigation·Sheetal R ModiDavid A Relman
Nov 22, 2014·Critical Care : the Official Journal of the Critical Care Forum·Marya D ZilberbergMarin H Kollef
Dec 30, 2014·Transplant Infectious Disease : an Official Journal of the Transplantation Society·L NesherR F Chemaly
Feb 15, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·J A SidlerA F Widmer
Mar 19, 2015·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Anthony D HarrisKerri A Thom
Mar 19, 2015·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Christopher S PepinAnthony D Harris
Mar 31, 2016·The Journal of Primary Prevention·James A Mercy, Alana M Vivolo-Kantor

❮ Previous
Next ❯

Citations

Nov 2, 2018·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Melinda M PettigrewJ Kristie Johnson
Feb 6, 2018·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Anthony D HarrisKerri A Thom
Jan 24, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Anthony D HarrisJ Kristie Johnson
Aug 15, 2017·Expert Review of Anti-infective Therapy·Alberto Enrico MaraoloIvan Gentile
Oct 1, 2020·Journal of Chemotherapy·Marko M FolicSlobodan M Jankovic
Sep 1, 2018·Antimicrobial Resistance and Infection Control·Pinyo RattanaumpawanVisanu Thamlikitkul
Apr 22, 2017·Antimicrobial Resistance and Infection Control·Fleur P PalingJan A J W Kluytmans
Aug 23, 2019·Journal of General Internal Medicine·N BlancoA D Harris
Feb 23, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Chen Wen XiaoGuo Lian Bao
Dec 18, 2020·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Stephanie M CabralAnthony D Harris
Aug 12, 2020·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Merlin MoniVidya P Menon

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Related Papers

Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
Sarah Tschudin-SutterTrish M Perl
Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
Julia A MessinaAntibacterial Resistance Leadership Group
Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
Rossana RosaL Silvia Munoz-Price
© 2021 Meta ULC. All rights reserved