PMID: 2495226Apr 1, 1989Paper

Pseudomonas aeruginosa cross-colonization and persistence in patients with cystic fibrosis. Use of a DNA probe

Epidemiology and Infection
C WolzG Döring

Abstract

To investigate cross-colonization with and persistence of Pseudomonas aeruginosa in cystic fibrosis (CF), 181 isolates from 76 CF patients were typed using a P. aeruginosa-specific DNA probe. Whereas sibling pairs predominantly harboured genotypically identical P. aeruginosa strains, all of the other patients harboured different strains. Seventy-nine per cent (22/31) of the infected CF patients harboured the same strains at the beginning and the end of a summer camp. A change of strains was seen in 10% (3/31) of the patients at the end of the camp. Forty-six per cent (6/13) of the patients who were apparently initially uninfected, acquired P. aeruginosa by the end of the period. Genotyping proved that strain change or acquisition was due to cross-colonization in four of nine cases. Very little P. aeruginosa was isolated from the inanimate environment. Persistence of P. aeruginosa after a temporary loss due to antibiotic therapy was seen in 12/16 paired patient strains before and after antibiotic therapy. Thus, suppression followed a flare-up seemed to occur in these patients rather than eradication and a new infection. When 35 patients were followed over a period of 6 months, 7 (20%) changed the strain in their sputum. Only one...Continue Reading

References

Jan 1, 1979·European Journal of Immunology·C GutiérrezM Kreisler
Jun 1, 1975·Journal of Clinical Microbiology·C H Zierdt, R L Williams
Jul 1, 1976·The Journal of Pediatrics·L R Laraya-CuasayN N Huang
Apr 1, 1988·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·T L Pitt
Jan 1, 1987·The Journal of Hospital Infection·D P Speert, M E Campbell
Jan 1, 1986·Annual Review of Microbiology·N HøibyP O Schiøtz
May 1, 1986·Infection and Immunity·M L VasilC C Grant
Feb 1, 1986·Journal of Clinical Pathology·K FonsecaT L Pitt
Apr 1, 1986·The Journal of Antimicrobial Chemotherapy·S S PedersenK Rosendal
Jan 1, 1987·The Journal of Infectious Diseases·J W OgleM L Vasil
Sep 1, 1987·Pediatric Pulmonology·M J ThomassenC F Doershuk
Apr 1, 1983·The Journal of Infectious Diseases·G DöringA Hofmann
Aug 1, 1982·The Journal of Pediatrics·D P SpeertS Damm

❮ Previous
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Citations

Jul 30, 1993·Clinica Chimica Acta; International Journal of Clinical Chemistry·B TümmlerH von der Hardt
Jan 26, 1996·Journal of Biotechnology·B von SpechtH Domdey
Sep 1, 1992·International Journal of Antimicrobial Agents·N Høiby
Jun 1, 1993·Epidemiology and Infection·G DöringC Wolz
Apr 9, 2010·Clinical Microbiology Reviews·John J Lipuma
Jan 17, 2004·Clinical Microbiology Reviews·Lisa Saiman, Jane Siegel
Oct 30, 2001·Journal of Clinical Microbiology·S SilbertH S Sader
Oct 3, 2002·American Journal of Respiratory and Critical Care Medicine·David S ArmstrongKeith Grimwood
Sep 3, 2013·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A Abdul WahabC H Klaassen
Feb 1, 1991·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·B OjeniyiV T Rosdahl
Feb 1, 1993·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·B OjeniyiN Høiby
May 1, 1990·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·B OjeniyiN Høiby
Oct 6, 1997·Journal of Clinical Periodontology·T C JohnsonK D Patil
Jun 1, 1996·Journal of Clinical Periodontology·B von Troil-LindénS Asikainen
Nov 20, 1998·The Journal of Infection·D L SmithD E Stableforth
Jul 1, 1993·The Journal of Hospital Infection·C L Poh, C C Yeo
Jul 16, 2014·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Lisa SaimanDavid J Weber
Jul 26, 2015·The Lancet. Respiratory Medicine·Timothy J KiddUNKNOWN ACPinCF Investigator Group
Jan 18, 2006·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Tacjana PresslerNiels Høiby
Oct 7, 2004·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Silvia CampanaMaurizio de Martino
Oct 7, 2004·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Gerd DöringUNKNOWN Consensus Study Group
Jun 26, 2001·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·G FlugeO T Storrøsten
Feb 13, 2001·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·F B SpenckerA C Rodloff
Feb 3, 2007·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·N MesarosF Van Bambeke
May 4, 2005·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Ralf-Peter Vonberg, Petra Gastmeier
Jun 7, 2003·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Lisa SaimanUNKNOWN Cystic Fibrosis Foundation
May 1, 1992·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·E BingenJ Elion
Oct 7, 2004·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·F P EdenboroughJ R W Govan
Apr 1, 1990·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·W KernG Döring
Oct 1, 1989·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·U B SchaadR Kraemer
Aug 1, 1996·The Pediatric Infectious Disease Journal·N HøibyC Koch
Jul 28, 2010·Expert Review of Respiratory Medicine·Ian J Clifton, Daniel G Peckham
Oct 27, 2017·American Journal of Respiratory and Critical Care Medicine·Nicholas J Simmonds, Andrew Bush

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