Pseudomonas aeruginosa Outbreak in a Neonatal Intensive Care Unit Attributed to Hospital Tap Water

Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
Cara Bicking KinseyCarolyn V Gould

Abstract

OBJECTIVE To investigate an outbreak of Pseudomonas aeruginosa infections and colonization in a neonatal intensive care unit. DESIGN Infection control assessment, environmental evaluation, and case-control study. SETTING Newly built community-based hospital, 28-bed neonatal intensive care unit. PATIENTS Neonatal intensive care unit patients receiving care between June 1, 2013, and September 30, 2014. METHODS Case finding was performed through microbiology record review. Infection control observations, interviews, and environmental assessment were performed. A matched case-control study was conducted to identify risk factors for P. aeruginosa infection. Patient and environmental isolates were collected for pulsed-field gel electrophoresis to determine strain relatedness. RESULTS In total, 31 cases were identified. Case clusters were temporally associated with absence of point-of-use filters on faucets in patient rooms. After adjusting for gestational age, case patients were more likely to have been in a room without a point-of-use filter (odds ratio [OR], 37.55; 95% confidence interval [CI], 7.16-∞). Case patients had higher odds of exposure to peripherally inserted central catheters (OR, 7.20; 95% CI, 1.75-37.30) and invasive v...Continue Reading

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Citations

Jan 7, 2018·Applied and Environmental Microbiology·Erika L EnglishMatthew J Wargo
Apr 29, 2018·Current Infectious Disease Reports·Geehan SuleymanAna Cecilia Bardossy
Dec 10, 2019·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Lina M ParraFernando J García
Dec 12, 2019·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Gina OdaMark Holodniy
Aug 24, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Matthew J Arduino
Dec 12, 2018·Médecine et maladies infectieuses·O PassouantJ Cousson
May 11, 2021·FEMS Microbiology Reviews·Andreu Coello PelegrinAlex van Belkum
Jun 3, 2021·Viruses·Ari KauppinenIlkka T Miettinen

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