Pseudomonas urinary tract infection in patients with spinal cord injury

The Journal of the American Paraplegia Society
J Z MontgomerieJ W Morrow

Abstract

Serum antibodies to P. aeruginosa were measured in 28 patients with spinal cord injury before and after the development of bacteriuria during their hospital rehabilitation. Serum IgG, IgA and IgM were measured against the infecting strain of P. aeruginosa isolated from the urine of each patient. After bacteriuria was detected, a significant increase (fourfold or greater) in IgG and/or IgA antibodies was found in nine patients (33%). This increase was significantly associated with leucocytosis. These observations indicate that bacteriuria with P. aeruginosa in patients with spinal cord injury is associated with a serum antibody response in a significant number of patients, indicating tissue invasion by this microorganism.

References

Nov 1, 1978·Infection and Immunity·T Nishi, K Tsuchiya
Apr 1, 1975·Proceedings of the Society for Experimental Biology and Medicine·S CohenR S Berk
Jan 1, 1985·The Journal of the American Paraplegia Society·R U Anderson
Jul 1, 1980·Infection and Immunity·J Z MontgomerieJ W Morrow
Jan 1, 1964·The Journal of Pathology and Bacteriology·R H GORRILL, S J DENAVASQUEZ

Citations

Oct 3, 2006·Expert Review of Anti-infective Therapy·Paolo Grossi, Daniela Dalla Gasperina
Aug 19, 2014·The Journal of Spinal Cord Medicine·Ali N Dana, William A Bauman

Related Concepts

Antibodies, Bacterial
Bacteriuria
Immunoglobulins
Pseudomonas aeruginosa
Pseudomonas Infections
Post-Traumatic Myelopathy
Urinary Tract Infection

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