Pseudophakic Macular Edema in Primary Open-Angle Glaucoma: A Prospective Study Using Spectral-Domain Optical Coherence Tomography

American Journal of Ophthalmology
Kyoung Min LeeHyunjoong Kim

Abstract

To determine the incidence of and risk factors for pseudophakic macular edema (PME) after uncomplicated cataract surgery in primary open-angle glaucoma (POAG) using spectral-domain optical coherence tomography (SDOCT). Cohort study. Macular retinal thickness was evaluated using SDOCT at 1 week before surgery and at 1, 3, 6, and 12 months postoperatively, in 70 POAG and 68 control eyes. Forty-three healthy subjects without impaired vision or cystoid PME were recruited separately as pilot samples to define significant PME. Significant PME was defined as an increase in the average thickness exceeding the mean + 3 standard deviations of the increase shown in the pilot samples. Significant PME (increase in the foveal 3-mm zone thickness of >19.5 μm) was observed in 31 (44%) eyes with POAG and in 14 (21%) control eyes (P = .003). The extent of PME was maximal at 3 months postoperatively and decreased gradually until 12 months. Regression tree analysis revealed that the risk of PME was the greatest in the POAG group using prostaglandin analogue (PGA) (odds ratio [OR] = 5.51), followed by POAG not using PGA (OR = 1.70), and control group (OR = 1.0). Risk factors for PME were younger age in all groups (OR = 1.07), systemic hypertension ...Continue Reading

Citations

Sep 16, 2017·Current Opinion in Ophthalmology·Laura H P WieldersRudy M M A Nuijts
Apr 7, 2019·Clinical & Experimental Ophthalmology·Jina V HanCharles Nj McGhee
Oct 1, 2019·Journal of Cataract and Refractive Surgery·Ghasem FakhraieAhmad Masoomi
Dec 6, 2019·Current Eye Research·Lotta IlveskoskiRaimo Tuuminen
Sep 13, 2018·European Journal of Ophthalmology·Lotta IlveskoskiRaimo Tuuminen
Aug 13, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·C J Doncel-FernándezG Castro-Luna
May 29, 2021·The British Journal of Ophthalmology·Nuwan NiyadurupolaDavid C Broadway

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