Pseudothrombocytopenia induced by a monoclonal IgM kappa platelet agglutinin

American Journal of Hematology
R H Hoyt, B G Durie

Abstract

Pseudothrombocytopenia is an in vitro phenomenon usually associated with anticoagulant (EDTA)-dependent IgG platelet agglutinins. A low Coulter platelet count was investigated in a 63-year-old woman with multiple sclerosis and a monoclonal IgM kappa gammopathy. An unusual type of EDTA- and temperature-independent IgM platelet agglutinin was identified by in vitro agglutination of donor platelets and was removed by immunoabsorption.

References

Dec 1, 1979·American Journal of Clinical Pathology·W A VeenhovenH O Nieweg
Oct 1, 1975·Scandinavian Journal of Haematology·M J MantH Sims
Feb 11, 1974·JAMA : the Journal of the American Medical Association·C R Kjeldsberg, E J Hershgold
Sep 11, 1980·The New England Journal of Medicine·N LatovE F Osserman
Feb 1, 1984·Mayo Clinic Proceedings·B A Payne, R V Pierre

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Citations

Dec 5, 2002·International Journal of Hematology·Shigeo ToyotaKazuo Dan
Mar 2, 2002·European Journal of Haematology·E S HatzipantelisN Gombakis
Jun 19, 2007·Laboratory Hematology : Official Publication of the International Society for Laboratory Hematology·M OreroF Carbonell
Jul 14, 2006·Mayo Clinic Proceedings·Bryan W Reed, Ronald S Go
May 23, 2015·Thrombosis and Haemostasis·I M Sánchez GuiuJ Rivera
Oct 17, 2012·Platelets·Arjan AlbersenPaul Hamberg

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