Pseudotumoral presentation of nodular regenerative hyperplasia of the liver: imaging in five patients including MR imaging

European Radiology
C CasillasJ Galant

Abstract

Nodular regenerative hyperplasia (NRH) of the liver is a condition characterized by multiple monoacinar regenerative nodules in the absence of fibrous septa. When these nodules become confluent they may be seen with sonography or CT. The appearance of these pseudotumoral pattern of NRH has been scarcely described with MRI. We present the imaging findings of five patients with NRH and a pseudotumoral form at sonography. Sonography depicted hyperechoic lesions in four patients and hypoechoic lesions in another. Computed tomography showed hypodense lesions with little contrast enhancement in two patients. Three patients showed subtle focal liver lesions on MRI: isointense in one, mildly hypointense in another, and minimally hyperintense in a patient with siderosis. The dynamic behavior at MRI was similar to the normal liver parenchyma. Hyperechoic lesions on sonography or hypodense lesions on CT, barely or not seen on MRI, can be indicative of NRH in an appropriate clinical setting.

References

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Citations

Mar 3, 2006·Current Gastroenterology Reports·Wojciech Blonski, K Rajender Reddy
Jun 21, 2005·Journal of Hepatology·Julia SeidererThomas Ochsenkühn
Oct 3, 2002·Topics in Magnetic Resonance Imaging : TMRI·Giovanni MoranaCarlo Procacci
Apr 9, 2005·Journal of Clinical Gastroenterology·Bo Yoon Choi, Mindie H Nguyen
Mar 24, 2010·AJR. American Journal of Roentgenology·Priyanka JhaFergus V Coakley
Apr 8, 2011·World Journal of Gastroenterology : WJG·Marek HartlebPiotr Milkiewicz
May 14, 2010·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Ellen M ChungRichard M Conran
Oct 29, 2008·Journal of the Chinese Medical Association : JCMA·Huay-Min WangShong-Ling Lin
Apr 6, 2002·Clinics in Liver Disease·Koenraad J Mortele, Pablo R Ros
Jan 22, 2015·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Sun Mi JinKyu Sung Rim
Dec 9, 2017·Abdominal Radiology·Demetrios PapadatosClaude B Sirlin
Aug 1, 2015·World Journal of Gastroenterology : WJG·Liliana ChioreanChristoph F Dietrich

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